Glyconanoparticles for Biomedical Applications

Title: Glyconanoparticles for Biomedical Applications

Volume: 14 Issue: 3

Author(s): Chang-Ming Dong

Affiliation:

Keywords: Glyconanoparticles, glycopolymers, biomolecular recognition, bioassays, targeted drug delivery, multivalent interactions, biological receptors, cell adhesion, carbohydrate-protein interactions, magnetic resonance imaging, colloidal stability, water-solubility, biodegradable, glycopolymer

Abstract: Over the past two decades, glycosylated nanoparticles (i.e., glyconanoparticles having sugar residues on the surface) received much attention for biomedical applications such as bioassays and targeted drug delivery. This minireview focuses on three aspects: (1) glycosylated gold nanoparticles, (2) glycosylated quantum dots, and (3) glyconanoparticles self-assembled from amphiphilic glycopolymers. The synthetic methods and the multivalent interactions between glyconanoparticles and lectins is shortly illustrated.

Cite this article as:

Dong Chang-Ming, Glyconanoparticles for Biomedical Applications, Combinatorial Chemistry & High Throughput Screening 2011; 14 (3) . https://dx.doi.org/10.2174/138620711794728716