Synthesis of Functionalized Chromenes from Meldrum’s Acid, 4- Hydroxycoumarin, and Ketones or Aldehydes

Title:Synthesis of Functionalized Chromenes from Meldrum’s Acid, 4- Hydroxycoumarin, and Ketones or Aldehydes

Volume: 13 Issue: 9

Author(s): Maryam Sabbaghan, Issa Yavari and Zinatossadat Hossaini

Affiliation:

Keywords: Chromene, proline, aqueous media, meldrum’s acid, 4-hydroxycoumarin

Abstract: An efficient synthesis of 4-alkyl-4-methyl-3,4-dihydro-2H,5H-pyrano[3,2-c]chromene-2,5-dione or 4-aryl-3,4- dihydro-2H,5H-pyrano[3,2-c]chromene-2,5-diones via reaction 4-hydroxycoumarin with Meldrum’s acid and ketones or aldehydes is described.

Cite this article as:

Sabbaghan Maryam, Yavari Issa and Hossaini Zinatossadat, Synthesis of Functionalized Chromenes from Meldrum’s Acid, 4- Hydroxycoumarin, and Ketones or Aldehydes, Combinatorial Chemistry & High Throughput Screening 2010; 13 (9) . https://dx.doi.org/10.2174/138620710792927358