The Combinatorial Synthesis of Bioactive Quinoxalines, Quinoxalinones and Quinoxalinols

Min      Lv; Hui      Xu

doi:10.2174/138620710790980513

Abstract

In the family of biologically active heterocyclic templates, quinoxalines, quinoxalinones, and quinoxalinols have received much attention owing to a wide range of their biological activities. As a consequence, approaches to the combinatorial synthesis of these compounds were surveyed, and this review discusses the solid-phase, solution-phase, solvent-free, and microwave-assisted parallel synthesis of quinoxalines, quinoxalinones, and quinoxalinols.

Keywords: Quinoxaline, quinoxalinone, quinoxalinol, heterocycle, solid-phase, solution-phase, solvent-free, microwave irradiation

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Combinatorial Chemistry & High Throughput Screening

Title: The Combinatorial Synthesis of Bioactive Quinoxalines, Quinoxalinones and Quinoxalinols

Volume: 13 Issue: 3

Author(s): Min Lv and Hui Xu

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Keywords: Quinoxaline, quinoxalinone, quinoxalinol, heterocycle, solid-phase, solution-phase, solvent-free, microwave irradiation

Abstract: In the family of biologically active heterocyclic templates, quinoxalines, quinoxalinones, and quinoxalinols have received much attention owing to a wide range of their biological activities. As a consequence, approaches to the combinatorial synthesis of these compounds were surveyed, and this review discusses the solid-phase, solution-phase, solvent-free, and microwave-assisted parallel synthesis of quinoxalines, quinoxalinones, and quinoxalinols.

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Lv Min and Xu Hui, The Combinatorial Synthesis of Bioactive Quinoxalines, Quinoxalinones and Quinoxalinols, Combinatorial Chemistry & High Throughput Screening 2010; 13 (3) . https://dx.doi.org/10.2174/138620710790980513