Enhanced Fluorescence of Curcumin on Plasmonic Platforms

Title: Enhanced Fluorescence of Curcumin on Plasmonic Platforms

Volume: 11 Issue: 2

Author(s): Anindita Mukerjee, Rafal Luchowski, Amalendu P. Ranjan, Sangram Raut, Jamboor K. Vishwanatha, Zygmunt Gryczynski and Ignacy Gryczynski

Affiliation:

Keywords: Fluorescence lifetime, metal enhanced fluorescence, photostability, plasmonic platforms, brightness, curcumin

Abstract: We report a significant increase of a curcumin (1,7-bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) fluorescence brightness when deposited on plasmonic platforms (self assembled silver nanostructures formed on the surface of silver semitransparent film). The enhancement of fluorescence intensity is accompanied by a strong decrease in fluorescence lifetime. Simultaneously, the increased photostability of curcumin, a pigment showing strong antiinflammatory, antioxidant and antitumorigenic activity, allows long-time detection and monitoring. We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin.

Cite this article as:

Mukerjee Anindita, Luchowski Rafal, Ranjan P. Amalendu, Raut Sangram, Vishwanatha K. Jamboor, Gryczynski Zygmunt and Gryczynski Ignacy, Enhanced Fluorescence of Curcumin on Plasmonic Platforms, Current Pharmaceutical Biotechnology 2010; 11 (2) . https://dx.doi.org/10.2174/138920110790909623