A Case of Topiramate-Induced Epistaxis

Title: A Case of Topiramate-Induced Epistaxis

Volume: 4 Issue: 3

Author(s): Giovanni Polimeni, Rosario Grugno, Antongiulio Vitetta, Francesco Cordici, Antonella Alagna, Achille P. Caputi and Placido Bramanti

Affiliation:

Keywords: Topiramate, epistaxis, calcium-channel blockers, blood clotting

Abstract: The current case describes epistaxis in a patient treated with a daily regimen of topiramate 100mg for migraine. The patient had not a past medical history of nosebleeds and laboratory parameters were within normal ranges. She was then advised to withdraw topiramate, and the epistaxis resolved within 12 hours after its discontinuation. Since then, the patient never complained other blood clotting disorders. The potential antiplatelet activity of topiramate is discussed.

Cite this article as:

Polimeni Giovanni, Grugno Rosario, Vitetta Antongiulio, Cordici Francesco, Alagna Antonella, Caputi P. Achille and Bramanti Placido, A Case of Topiramate-Induced Epistaxis, Current Drug Safety 2009; 4 (3) . https://dx.doi.org/10.2174/157488609789007001