Myelination in Bipolar Patients and the Effects of Mood Stabilizers on Brain Anatomy

Title: Myelination in Bipolar Patients and the Effects of Mood Stabilizers on Brain Anatomy

Volume: 15 Issue: 22

Author(s): Paolo Brambilla, Marcella Bellani, Ping-Hong Yeh and Jair C. Soares

Affiliation:

Keywords: Diffusion imaging, white matter, prefrontal cortex, hippocampus, amygdala, corpus callosum, lithium, valproate

Abstract: In this review, we debate the evidence for abnormal white matter microstructure and myelination in bipolar disorder, as mainly detected by diffusion tensor imaging (DTI) studies. The effects of mood stabilizers on white matter are discussed, based on available findings from human and animal studies. Last, perspectives in this field of research are also drawn.

Cite this article as:

Brambilla Paolo, Bellani Marcella, Yeh Ping-Hong and Soares C. Jair, Myelination in Bipolar Patients and the Effects of Mood Stabilizers on Brain Anatomy, Current Pharmaceutical Design 2009; 15 (22) . https://dx.doi.org/10.2174/138161209788957519