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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Mini-Review Article

Recent Advancements in Glycosylation Reactions: An Access to Privileged C- and S-Glycosides

In Press, (this is not the final "Version of Record"). Available online 06 August, 2024
Author(s): Ram Pratap Pandey, Bindu Tiwari, Anand Kumar Pandey and Nazar Hussain*
Published on: 06 August, 2024

DOI: 10.2174/0113852728322447240718054734

Price: $95

Abstract

Glycosylation reactions are central to carbohydrate chemistry due to their broad applications in drug development and biological probes. Despite presenting significant challenges and often requiring substantial amounts of promoters, these reactions yield value-added products of immense biological importance. The incorporation of transition metal catalysis in glycosylation reactions offers advantages, such as mild reaction conditions and enhanced selectivity. Currently, synthetic chemists are particularly interested in C- and S-glycosides because their glycosidic linkages exhibit greater metabolic stability compared to the more vulnerable Oglycosides. This review aims to explore recent advances in the synthesis of various structurally diverse and biologically relevant C- and S-glycosides, covering literature from 2019 to 2024.


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