Abstract
Chitosan (CS) is a natural polymer obtained by removing acetyl groups from chitin through alkaline hydrolysis. It possesses biodegradable properties and exhibits immunological, antibacterial, and wound-healing activities. This polysaccharide has undergone modification through radiation-induced graft copolymerization to broaden its application scope. The potential applications of CS can be expanded by introducing side chains through grafting. This article aims to review the innovative alternatives of gamma-graft-copolymerized CS and, for the first time, comprehensively examines the current applications of CS derivatives in dye removal, metal adsorption, antibacterial interventions, biomedical practices, drug delivery systems, and tissue engineering.
[http://dx.doi.org/10.3390/polym15071729] [PMID: 37050343]
[http://dx.doi.org/10.1007/s13399-022-02684-x]
[http://dx.doi.org/10.1016/j.ijbiomac.2024.130105] [PMID: 38346623]
[http://dx.doi.org/10.1016/j.aqrep.2024.102155]
[http://dx.doi.org/10.1016/j.foodchem.2023.136788] [PMID: 37467692]
[http://dx.doi.org/10.3390/ijms241310738] [PMID: 37445916]
[http://dx.doi.org/10.3390/polym15102235] [PMID: 37242810]
[http://dx.doi.org/10.1016/j.ijbiomac.2024.130851] [PMID: 38484821]
[http://dx.doi.org/10.1016/j.ijbiomac.2024.130825] [PMID: 38492705]
[http://dx.doi.org/10.1021/acsabm.3c00814] [PMID: 38442406]
[http://dx.doi.org/10.1016/j.carbpol.2024.121952] [PMID: 38494217]
[http://dx.doi.org/10.1021/sc500634p]
[http://dx.doi.org/10.1016/j.molliq.2024.124625]
[http://dx.doi.org/10.1080/00222348.2024.2310438]
[http://dx.doi.org/10.1002/adhm.202302877] [PMID: 38041691]
[http://dx.doi.org/10.1016/j.matpr.2023.01.366]
[http://dx.doi.org/10.1088/1742-6596/2431/1/012069]
[http://dx.doi.org/10.1080/25740881.2023.2263077]
[http://dx.doi.org/10.1016/j.radphyschem.2023.111197]
[http://dx.doi.org/10.1016/j.radphyschem.2023.110892]
[http://dx.doi.org/10.1080/00222338208062409]
[http://dx.doi.org/10.1016/S0969-806X(00)00389-3]
[http://dx.doi.org/10.1016/j.mtchem.2022.100780]
[http://dx.doi.org/10.1002/marc.200400288]
[http://dx.doi.org/10.1016/S0960-8524(03)00171-8] [PMID: 14592745]
[http://dx.doi.org/10.1002/(SICI)1097-0290(19990420)63:2<154::AID-BIT4>3.0.CO;2-R] [PMID: 10099592]
[http://dx.doi.org/10.1002/1097-0290(20001205)70:5<564::AID-BIT11>3.0.CO;2-W] [PMID: 11042553]
[http://dx.doi.org/10.1016/j.molcatb.2014.10.014]
[http://dx.doi.org/10.1016/j.ijbiomac.2023.123498] [PMID: 36731699]
[http://dx.doi.org/10.3390/foods12193688] [PMID: 37835341]
[http://dx.doi.org/10.1016/j.eurpolymj.2023.112670]
[http://dx.doi.org/10.1016/j.ijbiomac.2023.123395] [PMID: 36702225]
[http://dx.doi.org/10.1007/s00289-023-04682-z]
[http://dx.doi.org/10.1016/j.foodchem.2023.136886] [PMID: 37499506]
[http://dx.doi.org/10.1021/acs.molpharmaceut.3c00031] [PMID: 37093958]
[http://dx.doi.org/10.1021/acsomega.3c02143] [PMID: 37692209]
[http://dx.doi.org/10.1016/j.seppur.2023.125213]
[http://dx.doi.org/10.1016/j.carbpol.2023.120926] [PMID: 37173025]
[http://dx.doi.org/10.1108/PRT-12-2021-0137]
[http://dx.doi.org/10.1016/j.carbpol.2005.07.017]
[http://dx.doi.org/10.1016/j.ijpharm.2010.05.034] [PMID: 20562002]
[http://dx.doi.org/10.1007/s41061-016-0092-5] [PMID: 27995526]
[http://dx.doi.org/10.1007/s13762-023-05244-6]
[http://dx.doi.org/10.1016/j.matpr.2024.01.031]
[http://dx.doi.org/10.1080/87559129.2021.1950176]
[http://dx.doi.org/10.1016/j.ijbiomac.2023.123716] [PMID: 36801297]
[http://dx.doi.org/10.1016/j.ijbiomac.2020.09.060] [PMID: 32949625]
[PMID: 38415441]
[http://dx.doi.org/10.1016/j.ijbiomac.2023.124915] [PMID: 37211080]
[http://dx.doi.org/10.2174/1381612829666230524153002] [PMID: 37226781]
[http://dx.doi.org/10.1080/01932691.2019.1614035]
[http://dx.doi.org/10.1016/j.colsurfb.2015.10.036] [PMID: 26551867]
[http://dx.doi.org/10.1016/j.synthmet.2009.07.006]
[http://dx.doi.org/10.1016/j.ijbiomac.2021.03.134] [PMID: 33775765]
[http://dx.doi.org/10.1016/j.carbpol.2021.117975] [PMID: 33858572]
[http://dx.doi.org/10.1016/j.radphyschem.2008.05.002]
[http://dx.doi.org/10.1016/j.radphyschem.2005.03.005]
[http://dx.doi.org/10.1002/app.1994.070530814]
[http://dx.doi.org/10.1007/s13233-018-6100-6]
[http://dx.doi.org/10.1016/j.radphyschem.2004.04.029]
[http://dx.doi.org/10.1109/ISBEIA.2012.6422950]
[http://dx.doi.org/10.1002/app.28618]
[http://dx.doi.org/10.1002/(SICI)1097-4628(19971031)66:5<869::AID-APP7>3.0.CO;2-T]
[http://dx.doi.org/10.1016/j.polymdegradstab.2009.10.007]
[http://dx.doi.org/10.1016/j.radphyschem.2011.11.056]
[http://dx.doi.org/10.1016/S0144-8617(97)00260-9]
[http://dx.doi.org/10.1016/j.radphyschem.2011.10.029]
[http://dx.doi.org/10.1016/j.radphyschem.2003.10.012]
[http://dx.doi.org/10.1016/j.radphyschem.2011.12.047]
[http://dx.doi.org/10.1134/S0965545X20060012]
[http://dx.doi.org/10.1016/j.ijbiomac.2019.07.033] [PMID: 31284002]
[http://dx.doi.org/10.1002/app.42522]
[http://dx.doi.org/10.1016/j.biortech.2007.08.014] [PMID: 17888656]
[http://dx.doi.org/10.1039/C1RA00473E]
[http://dx.doi.org/10.1016/j.chemosphere.2006.06.072] [PMID: 16904161]
[http://dx.doi.org/10.1080/25740881.2020.1738469]
[http://dx.doi.org/10.1016/j.ijbiomac.2018.10.107] [PMID: 30340005]
[http://dx.doi.org/10.1016/j.radphyschem.2017.11.018]
[http://dx.doi.org/10.1016/j.ijbiomac.2020.08.120] [PMID: 32805290]
[http://dx.doi.org/10.1080/02757540.2021.1886280]
[http://dx.doi.org/10.1007/s10967-014-3149-3]
[http://dx.doi.org/10.1016/j.radphyschem.2011.06.013]
[http://dx.doi.org/10.1002/masy.201550323]
[http://dx.doi.org/10.1080/03602550701869984]
[http://dx.doi.org/10.1088/1757-899X/316/1/012007]
[http://dx.doi.org/10.3390/polym13162641] [PMID: 34451181]
[http://dx.doi.org/10.1007/s00289-008-0952-4]
[http://dx.doi.org/10.1016/j.jhazmat.2011.03.055] [PMID: 21497016]
[http://dx.doi.org/10.1016/j.ijbiomac.2021.09.196] [PMID: 34619272]
[http://dx.doi.org/10.1007/s12665-017-6780-9]
[http://dx.doi.org/10.1002/app.13120]
[http://dx.doi.org/10.1016/j.msec.2016.12.127] [PMID: 28254305]
[http://dx.doi.org/10.1016/j.radphyschem.2004.10.007]
[http://dx.doi.org/10.1002/app.10812]
[http://dx.doi.org/10.1016/j.carbpol.2016.08.083] [PMID: 27702516]
[http://dx.doi.org/10.3390/membranes11080561] [PMID: 34436324]
[http://dx.doi.org/10.1080/10601320701235891]
[http://dx.doi.org/10.1016/j.msec.2016.11.001] [PMID: 27987797]
[http://dx.doi.org/10.3390/ma11122535] [PMID: 30551595]
[http://dx.doi.org/10.1016/j.radphyschem.2013.06.026]
[http://dx.doi.org/10.1016/j.nimb.2007.09.013]
[http://dx.doi.org/10.1016/j.radphyschem.2019.108656]
[http://dx.doi.org/10.1177/0885328219890071] [PMID: 31771402]
[http://dx.doi.org/10.1080/15538362.2020.1740909]