Abstract
Introduction: A stent retriever (SR) is widely used in mechanical thrombectomy (MT) for M2 segment occlusion. However, the suitable size of SR in M2 occlusion remains unclear. Therefore, we aimed to compare 4 mm-sized SR with 3 mm-sized SR in M2 occlusion.
Methods: Patients who underwent MT with SR for M2 occlusion were dichotomized into 4×20 mm SR and 3×20 mm SR groups. Then, 1:1 propensity score matching was performed. The M2 segment was divided into proximal and distal segments according to the occlusion site. Subgroup analysis was then performed for each cohort.
Results: A total of 111 patients were enrolled, with 4×20 mm SR and 3×20 mm SR applied in 72 (64.9%) and 39 (35.1%) cases, respectively. In propensity score matching, mean number of stent passages for reperfusion was significantly lower in the 4×20 mm SR group than in the 3×20 mm SR group (1.5 ± 0.8 vs. 2.1 ± 1.1; p = 0.004). First-pass reperfusion (FPR) was more highly achieved in the 4×20 mm SR group than in the 3×20 mm SR group (52.6% vs. 42.1%; p = 0.007). In both proximal and distal occlusion cohorts, the 4 mm SR group showed lower mean number of SR passage (p = 0.004 and p = 0.003, respectively) and higher FPR rate than the 3 mm SR group (p = 0.003 and p = 0.007, respectively).
Conclusion: In MT for M2 occlusion, 4×20 mm SR enables an effective procedure with lesser SR passage for reperfusion and a higher rate of FPR than 3×20 mm SR.
[http://dx.doi.org/10.1056/NEJMoa1411587] [PMID: 25517348]
[http://dx.doi.org/10.1056/NEJMoa1414792] [PMID: 25671797]
[http://dx.doi.org/10.1056/NEJMoa1414905] [PMID: 25671798]
[http://dx.doi.org/10.1056/NEJMoa1503780] [PMID: 25882510]
[http://dx.doi.org/10.1056/NEJMoa1415061] [PMID: 25882376]
[http://dx.doi.org/10.1001/jama.2017.9644] [PMID: 28763550]
[http://dx.doi.org/10.1016/S0140-6736(19)30297-1] [PMID: 30860055]
[http://dx.doi.org/10.1016/j.jocn.2012.10.037] [PMID: 23835465]
[http://dx.doi.org/10.1016/S0140-6736(16)00163-X] [PMID: 26898852]
[http://dx.doi.org/10.1177/17474930231184369] [PMID: 37306490]
[http://dx.doi.org/10.1161/STROKEAHA.120.028956] [PMID: 32757757]
[http://dx.doi.org/10.1002/ana.26331] [PMID: 35184327]
[http://dx.doi.org/10.3174/ajnr.A4591] [PMID: 26564442]
[http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105018] [PMID: 32807433]
[http://dx.doi.org/10.2174/1567202620666221220090548] [PMID: 36537606]
[http://dx.doi.org/10.7461/jcen.2021.E2020.11.002] [PMID: 34492752]
[http://dx.doi.org/10.1016/j.wneu.2022.06.065] [PMID: 35750141]
[http://dx.doi.org/10.1001/jamaneurol.2016.2773] [PMID: 27617425]
[http://dx.doi.org/10.1136/jnis-2022-019898] [PMID: 36990689]
[http://dx.doi.org/10.2174/1567202620666230710114443] [PMID: 37431897]
[http://dx.doi.org/10.1136/neurintsurg-2016-012466] [PMID: 27382124]
[http://dx.doi.org/10.1136/neurintsurg-2019-014990] [PMID: 31243066]
[http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105389] [PMID: 33096489]
[http://dx.doi.org/10.1136/neurintsurg-2018-013918] [PMID: 29858398]
[http://dx.doi.org/10.1056/NEJMoa0804656] [PMID: 18815396]
[http://dx.doi.org/10.1016/j.jocn.2020.04.079] [PMID: 32327379]
[http://dx.doi.org/10.3340/jkns.2020.0046] [PMID: 32759627]
[http://dx.doi.org/10.1016/j.wneu.2022.07.001] [PMID: 35809841]
[http://dx.doi.org/10.2174/1567202616666191023154956] [PMID: 31702492]
[http://dx.doi.org/10.2174/1567202620666221103101512] [PMID: 36330622]
[http://dx.doi.org/10.1136/jnis-2023-020114] [PMID: 37076277]
[http://dx.doi.org/10.1159/000210432] [PMID: 19342825]
[http://dx.doi.org/10.2174/1567202620666230404125627] [PMID: 37021421]
[http://dx.doi.org/10.1136/neurintsurg-2013-011022] [PMID: 24385554]
[http://dx.doi.org/10.3340/jkns.2021.0158] [PMID: 35728980]
[http://dx.doi.org/10.2174/1567202620666230201121411] [PMID: 36725823]
[http://dx.doi.org/10.1136/neurintsurg-2017-013394] [PMID: 28963362]
[http://dx.doi.org/10.1161/STROKEAHA.115.010044] [PMID: 26374483]
[http://dx.doi.org/10.3174/ajnr.A4222] [PMID: 25634721]
[http://dx.doi.org/10.1016/j.wneu.2017.08.043] [PMID: 28826861]
[http://dx.doi.org/10.1136/neurintsurg-2016-012322] [PMID: 26975839]
[http://dx.doi.org/10.1016/S0140-6736(12)61299-9] [PMID: 22932714]
[http://dx.doi.org/10.1016/S0140-6736(12)61384-1] [PMID: 22932715]
[http://dx.doi.org/10.1136/neurintsurg-2014-011613] [PMID: 25948592]
[http://dx.doi.org/10.1136/neurintsurg-2015-012213] [PMID: 27016318]