Abstract
Background: Avascular necrosis (AVN) is a potentially serious multifactorial disease. In COVID-19 patients, AVN of many bones has been reported. Usually, the condition is linked to steroid therapy. In this case report, we describe our experience with bilateral AVN of femoral heads in an elderly patient months after being cured of COVID-19 infection without the use of steroids.
Case Presentation: A 68-year-old male was referred to the outpatient clinic of the rheumatology and rehabilitation department for progressive bilateral hip pain starting on the left side 5 months ago. An extensive review of the patient’s medical history identified documented COVID-19 infection that required hospitalization 9 months before presentation. Multiplanar MRI with fat suppression of both hips showed ill-defined areas of abnormal signal intensity affecting the left femoral head, neck and intertrochanteric regions with associated subchondral fissuring and mild joint effusion. A similar smaller area was also seen affecting the postero-superior aspect of the right femoral head.
Conclusion: AVN in COVID-19 patients can be encountered even in the absence of steroid therapy.
Graphical Abstract
[http://dx.doi.org/10.1038/s41579-022-00846-2]
[http://dx.doi.org/10.2174/1389557523666221116154907] [PMID: 36397624]
[http://dx.doi.org/10.1016/S2666-7568(22)00245-8] [PMID: 36480981]
[http://dx.doi.org/10.1016/j.hcl.2022.03.011] [PMID: 36244704]
[http://dx.doi.org/10.2147/DDDT.S298691] [PMID: 33692615]
[http://dx.doi.org/10.52312/jdrs.2023.895] [PMID: 36700267]
[http://dx.doi.org/10.7759/cureus.29982] [PMID: 36381929]
[http://dx.doi.org/10.2106/JBJS.CC.21.00629] [PMID: 35202008]
[http://dx.doi.org/10.1186/s13018-022-03192-4] [PMID: 35668523]
[http://dx.doi.org/10.1016/j.amsu.2022.104226] [PMID: 35936570]
[http://dx.doi.org/10.1016/j.amsu.2022.104753] [PMID: 36168319]
[http://dx.doi.org/10.7759/cureus.29976] [PMID: 36381920]
[http://dx.doi.org/10.3389/fmed.2022.970423] [PMID: 36017003]
[http://dx.doi.org/10.1016/S0140-6736(20)32656-8] [PMID: 33428867]
[http://dx.doi.org/10.3389/fimmu.2022.992384] [PMID: 36466841]
[http://dx.doi.org/10.1177/00033197231153204] [PMID: 36652923]
[http://dx.doi.org/10.3389/fmed.2021.714426] [PMID: 34368201]
[http://dx.doi.org/10.1093/pm/pnab341] [PMID: 34931670]
[http://dx.doi.org/10.3390/biomedicines9121931] [PMID: 34944747]
[http://dx.doi.org/10.3389/fmed.2023.1085988] [PMID: 36744129]
[http://dx.doi.org/10.3389/fmed.2021.663670] [PMID: 34490284]