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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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Research Article

Ruthenium-catalyzed Olefin Metathesis in Water using Thermo-responsive Diblock Copolymer Micelles

Author(s): Noriyuki Suzuki*, Ken Watanabe, Chirika Takahashi, Yuko Takeoka and Masahiro Rikukawa

Volume 27, Issue 15, 2023

Published on: 04 October, 2023

Page: [1347 - 1356] Pages: 10

DOI: 10.2174/1385272827666230911115809

Price: $65

Abstract

Ruthenium-catalyzed olefin metathesis reactions were conducted in water with thermoresponsive block copolymers forming micelles. The block copolymers were prepared by living radical polymerization and consisted of a thermo-responsive and hydrophilic segments. The former segment included poly(N-isopropylacrylamide) or poly(N,N-diethylacrylamide), and the latter poly(sodium 4-styrene sulfonate), poly(sodium 2-acrylamido-2-methylpropanesulfonate) or poly(ethylene glycol). Homometathesis, cross-metathesis and ring-closing metathesis reactions proceeded to afford the products in moderate to good yields. Extraction efficiency from the reaction mixture was also studied.

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