Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine

Alberto      Coelho; Abel      Crespo; Franco      Fernandez; PierFrancesco      Biagini; Angela      Stefanachi; Eddy      Sotelo

doi:10.2174/138620708786734253

Abstract

Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.

Keywords: Supported reagents, TMG, base

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Combinatorial Chemistry & High Throughput Screening

Title: Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine

Volume: 11 Issue: 10

Author(s): Alberto Coelho, Abel Crespo, Franco Fernandez, PierFrancesco Biagini, Angela Stefanachi and Eddy Sotelo

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Keywords: Supported reagents, TMG, base

Abstract: Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.

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Coelho Alberto, Crespo Abel, Fernandez Franco, Biagini PierFrancesco, Stefanachi Angela and Sotelo Eddy, Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine, Combinatorial Chemistry & High Throughput Screening 2008; 11 (10) . https://dx.doi.org/10.2174/138620708786734253