Temporin antibiotic peptides: A review and derivation of a consensus sequence

Title:Temporin antibiotic peptides: A review and derivation of a consensus sequence

Volume: 7 Issue: 6

Author(s): D. Wade*, A. Silveira, J. Silberringb, P. Kuuselac and H. Lankinen

Affiliation:

• Atherosclerosis Research Unit, King GustafV Research Institute, Karolinska Institutet, Karolinska Hospital - M9, 171 76 Stockholm, Sweden

Abstract: The temporins are a group of small, linear, basic, highly hydrophobic, antibiotic, peptide amides that were originally isolated from the skin of the European red frog, Rana temporaria. During the past decade, 30 temporin or temporin-like peptides have been isolated from the skins of Anurans. This article presents a brief review of the temporin literature, an analysis of the amino acid sequences of temporins and temporin-like peptides, and the derivation of a composite or consensus sequence, [FLP(I/L)IASLL(S/G)KLL-am].

Cite this article as:

Wade D.*, Silveira A., Silberringb J., Kuuselac P. and Lankinen H., Temporin antibiotic peptides: A review and derivation of a consensus sequence, Protein & Peptide Letters 2000; 7 (6) . https://dx.doi.org/10.2174/092986650706221207144422