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CNS & Neurological Disorders - Drug Targets

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ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

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Research Article

Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities

Author(s): Jasna Jančić, Janko Zeković, Mila Ćetković, Blažo Nikolić, Nikola Ivančević, Danijela Vučević, Zorica Nešić, Srđan Milovanović, Miroslav Radenković and Janko Samardžić*

Volume 22, Issue 9, 2023

Published on: 03 October, 2022

Page: [1369 - 1377] Pages: 9

DOI: 10.2174/1871527321666220831095204

open access plus

Abstract

Background: Peripheral facial nerve palsy is a relatively frequent, rather idiopathic, and isolated nonprogressive disorder with a tendency toward spontaneous recovery in children. It is primarily characterized by unilateral paresis or paralysis of the mimic musculature, affecting verbal communication, social interactions, and quality of life.

Objective: This study aimed to evaluate the clinical aspects and efficacy of different therapeutic modalities in the population of children and adolescents with acute peripheral facial nerve palsy, the quality and recovery rate in comparison to different therapy modalities and etiological factors as well as to determine parameters of recovery according to the age of patients.

Methods: The retrospective study included children and adolescents (n=129) with an acute onset of peripheral facial nerve palsy, diagnosed and treated in the Clinic of Neurology and Psychiatry for Children and Youth in Belgrade (2000-2018). The mean age of the patients was 11.53 years (SD±4.41). Gender distribution was 56.6% female and 43.4% male patients.

Results: There were 118 (91.5%) patients with partial and 11 (8.5%) patients with complete paralysis. Left-sided palsy occurred in 67 (51.9%) patients, right-sided in 58 (45.0%), while there were 4 (3.1%) bilateral paralyses. The most common etiological factor was idiopathic (Bell’s palsy), i.e., 74 (57.4%) patients, followed by middle ear infections, i.e., 16 (12.4%). Regardless of etiology, age, and therapy protocols, there was a significant recovery in most of the patients (p<0.001), without significant differences in recovery rate. Comparison of inpatient and outpatient populations showed significant differences regarding the number of relapses, the severity of clinical presentation, and the recovery rate in relation to etiology.

Conclusion: Bell’s palsy is shown to be the most common cause of peripheral facial nerve palsy in children and adolescents, regardless of gender. It is followed by mid-ear infections, respiratory infections, and exposure to cold. Most children and adolescents recovered three weeks after initial presentation, regardless of etiology, age, and therapy.

Keywords: Peripheral facial nerve palsy, bell’s palsy, house-brackmann scale, clinical characteristics, children, adolescents, inpatients, outpatients.

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