Chemically-Modified HA for Therapy and Regenerative Medicine

Glenn   D.   Prestwich; Jing-wen      Kuo

doi:10.2174/138920108785161523

Abstract

Hyaluronan (HA) is a very useful polymer, but its properties sometimes need to be altered or enhanced by chemical modification for biomedical applications. A wide variety of HA derivatives are currently used for eye surgery, joint viscoelastic supplementation, and anti-adhesion films. The future promises to deliver new classes of HA-based reagents as well as new polymers that can be used in situ with living cells or within the body.

Keywords: Cross-linking, gels, scaffolds, biomaterials

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Current Pharmaceutical Biotechnology

Title: Chemically-Modified HA for Therapy and Regenerative Medicine

Volume: 9 Issue: 4

Author(s): Glenn D. Prestwich and Jing-wen Kuo

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Keywords: Cross-linking, gels, scaffolds, biomaterials

Abstract: Hyaluronan (HA) is a very useful polymer, but its properties sometimes need to be altered or enhanced by chemical modification for biomedical applications. A wide variety of HA derivatives are currently used for eye surgery, joint viscoelastic supplementation, and anti-adhesion films. The future promises to deliver new classes of HA-based reagents as well as new polymers that can be used in situ with living cells or within the body.

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Prestwich D. Glenn and Kuo Jing-wen, Chemically-Modified HA for Therapy and Regenerative Medicine, Current Pharmaceutical Biotechnology 2008; 9 (4) . https://dx.doi.org/10.2174/138920108785161523