Nonfocal Symptoms in Patients with Transient Ischemic Attack and Association with Stroke Risk

Title:Nonfocal Symptoms in Patients with Transient Ischemic Attack and Association with Stroke Risk

Volume: 18 Issue: 5

Author(s): Shuxiang Yang, Lu Zhao*, Lulu Pei, Shuang Cao, Yuan Gao, Hui Fang, Kai Liu, Shilei Sun, Jun Wu, Bo Song and Yuming Xu

Affiliation:

• The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province,China

Keywords: Transient ischemic attack, nonfocal symptoms, stroke, prognosis, diffusion-weighted imaging

Abstract: Background and Objective: Patients with transient ischemic attack（TIA）occasionally showed nonfocal symptoms, such as decreased consciousness, amnesia and non-rotatory dizziness. This study intended to evaluate the effect of nonfocal symptoms on the prognosis of patients with TIA.

Methods: Data from the prospective hospital-based TIA database of the First Affiliated Hospital of Zhengzhou University were analyzed. The predictive outcome was stroke occurrence at 1 year. Cumulative risks of stroke in patients with and without nonfocal symptoms were estimated with Kaplan-Meier models.

Results: We studied 1384 patients with TIA (842 men; mean age, 56±13 years), including 450 (32.5%) with nonfocal symptoms. In the first year after TIA, stroke occurred in 168（12.1%） patients. There was no difference in the risk of stroke between patients with both focal and nonfocal symptoms and patients with focal symptoms alone (11.8% vs 12.4%, log-rank; P=0.691).

Conclusions: The occurrence of nonfocal symptoms did not increase the risk of stroke at one-year follow-up compared to the occurrence of focal symptoms alone.

Cite this article as:

Yang Shuxiang, Zhao Lu *, Pei Lulu , Cao Shuang , Gao Yuan , Fang Hui , Liu Kai , Sun Shilei , Wu Jun , Song Bo and Xu Yuming , Nonfocal Symptoms in Patients with Transient Ischemic Attack and Association with Stroke Risk, Current Neurovascular Research 2021; 18 (5) . https://dx.doi.org/10.2174/1567202619666211217124919