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Review Article

一篇关于长链非编码RNA在胃癌中的治疗、诊断和预后价值的最新综述

卷 29, 期 19, 2022

发表于: 14 January, 2022

页: [3471 - 3482] 页: 12

弟呕挨: 10.2174/0929867328666211115121019

价格: $65

摘要

长链非编码RNA(lncRNAs)作为一组新的非编码RNA，可以显著地调节各种生物过程。下调肿瘤抑制lncRNAs和上调致癌lncRNAs(onco-lncRNAs)与胃癌(GC)的发展有关。这些失调与胃癌中化学敏感性降低、抑制细胞凋亡和肿瘤迁移增加有关。此外，越来越多的证据表明，lncRNA可以作为一种有价值的诊断和预后生物标志物，其表达水平与患者的临床病理特征显著相关。本研究旨在回顾肿瘤抑制lncRNA和onco-lncRNAs在胃癌发展中的最新发现，并强调其在治疗胃癌细胞中的治疗、诊断和预后价值。此外，它还旨在强调lncRNA治疗GC的未来发展方向。

关键词: lncRNA、胃癌、生物标志物、肿瘤抑制、致癌、诊断、预后。

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