Naturally Derived Glycosides with Potential Activity against Staphylococcus Aureus

Title:Naturally Derived Glycosides with Potential Activity against Staphylococcus Aureus

Volume: 21 Issue: 27

Author(s): Yulin Zou and Wei Fang*

Affiliation:

• Department of Emergency, Zhuji People’s Hospital of Zhejiang Province, Zhuji, Shaoxing, 311800,China

Keywords: Glycosides, Natural-derived, S. aureus, Methicillin-resistant S. aureus, Drug resistance, DNA.

Abstract: Staphylococcus aureus (S. aureus) is one of the most common pathogens and implicated in a wide range of infections. It is responsible for a high rate of morbidity and mortality and has already posed a great burden on the healthcare system. S. aureus strains have already generated resistance to almost all available antibiotics, due to which the World Health Organization stratified S. aureus as a high tier priority II pathogen. Glycosides, the secondary metabolites of many plants in nature, possess a variety of pharmacological properties, including antibacterial activity against S. aureus. The structural and mechanistic diversity make glycosides useful weapons against S. aureus. This review summarizes the recent studies on naturally-derived glycosides and provides a comprehensive summary regarding the status of the resources and the anti-S. aureus potential.

Cite this article as:

Zou Yulin and Fang Wei *, Naturally Derived Glycosides with Potential Activity against Staphylococcus Aureus, Current Topics in Medicinal Chemistry 2021; 21 (27) . https://dx.doi.org/10.2174/1568026621666211015091539