Abstract
Cyclodextrin (CD) polymers are covalently linked hollow structures that are a network of less flexible macrocycles. They can be divided into two main groups: a) soluble (CDPS); and b) insoluble (CDPIS) polymers. These two types are generally prepared in a similar reaction, and the CD/reagent ratio determines the final properties of the reaction product. Changing this ratio of the generally bifunctionalized crosslinking agent and reaction conditions can lead to CDPS or CDPIS. The classical synthetic way in solution often leads to partial reagent(s) degradation, which frequently results in poorly reproducible products. At the same CD/reagent ratio, the reaction in solution yielded soluble CD polymers, whereas the reaction under mechanochemical conditions produced insoluble CD polymers. Usually, further derivatization of CDPIS or polymerization of derivatized CDs can be difficult or even impossible. The reactivity of hydroxyl groups in methylated CDs is limited so that reactions generally require high-boiling solvents and/or a large excess of reagent. This paper presents an economical, reproducible, and well-scalable synthetic method for producing some insoluble CD polymers. The physicochemical and adsorption properties of CDPIS prepared in a planetary ball mill are also compared.
Keywords: Epichlorohydrin, insoluble polymer, methylated β-cyclodextrin, planetary ball mill, mechanochemistry, adsorption isotherms, dyes, swelling.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Books
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
20