New Horizons in the Treatment of Neurological Disorders with Tailorable Gold Nanoparticles

Title:New Horizons in the Treatment of Neurological Disorders with Tailorable Gold Nanoparticles

Volume: 22 Issue: 12

Author(s): Farheen , Md. Asad Khan*, Ghulam Md. Ashraf, Anwar L. Bilgrami and M. Moshahid A. Rizvi

Affiliation:

• Department of Biochemistry, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India

Keywords: Neurodegeneration, blood brain barrier, nanotechnology, gold nanoparticles, neurological disorders, therapeutic drug approaches.

Abstract: Neurological disorders, such as epilepsy, dementia, Parkinson’s disease and Alzheimer’s disease, occur due to disorganization of the neurons in the nervous system. Disturbances in the nervous system cause problems with the memory, senses and moods. In order to treat such disorders, scientists have been working extensively, utilizing different approaches. Nanoneurotechnology has emerged as a promising tool to manage these complicated disorders, where nanoparticles with their tunable properties such as size, shape, increased solubility, biodegradability, surface area and sharp penetration through the biological barriers, target the central nervous system. This technology targets damaged neurons without affecting healthy neurons and the Blood-Brain Barrier (BBB). In this review, we discuss neurological disorders and challenges in their diagnosis and treatment by emphasizing on the role of tailorable gold nanoparticles in therapeutic drug approaches.

Cite this article as:

Farheen , Khan Asad Md. *, Ashraf Md. Ghulam , Bilgrami L. Anwar and Rizvi Moshahid A. M. , New Horizons in the Treatment of Neurological Disorders with Tailorable Gold Nanoparticles, Current Drug Metabolism 2021; 22 (12) . https://dx.doi.org/10.2174/1389200222666210525123416