Abstract
Alzheimer’s Disease (AD) is one of the major neurodegenerative disorders. Deposition of amyloid fibrils and tau protein is associated with various pathological symptoms. Currently, limited medication is available for AD treatment. Most of the drugs are basically cholinesterase inhibitors and associated with various side effects. Natural plant products have shown potential as a therapeutic agent for the treatment of AD symptoms. A variety of secondary metabolites such as flavonoids, tannins, terpenoids, alkaloids, and phenols are used to reduce the progression of the disease. Plant products have fewer or no side effects and are easily available. The present review gives a detailed account of the potential of natural plant products against AD symptoms.
Keywords: Alzheimer's disease, natural plant products, pathogenesis, treatment, AD symptoms, secondary metabolites.
Graphical Abstract
CNS & Neurological Disorders - Drug Targets
Title:Role of Natural Plant Products Against Alzheimer’s Disease
Volume: 20 Issue: 10
Author(s): Himanshi Varshney and Yasir Hasan Siddique*
Affiliation:
- Drosophila Transgenic Laboratory, Section of Genetics, Department of Zoology, Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh,India
Keywords: Alzheimer's disease, natural plant products, pathogenesis, treatment, AD symptoms, secondary metabolites.
Abstract: Alzheimer’s Disease (AD) is one of the major neurodegenerative disorders. Deposition of amyloid fibrils and tau protein is associated with various pathological symptoms. Currently, limited medication is available for AD treatment. Most of the drugs are basically cholinesterase inhibitors and associated with various side effects. Natural plant products have shown potential as a therapeutic agent for the treatment of AD symptoms. A variety of secondary metabolites such as flavonoids, tannins, terpenoids, alkaloids, and phenols are used to reduce the progression of the disease. Plant products have fewer or no side effects and are easily available. The present review gives a detailed account of the potential of natural plant products against AD symptoms.
Export Options
About this article
Cite this article as:
Varshney Himanshi and Siddique Hasan Yasir *, Role of Natural Plant Products Against Alzheimer’s Disease, CNS & Neurological Disorders - Drug Targets 2021; 20 (10) . https://dx.doi.org/10.2174/1871527320666210420135437
DOI https://dx.doi.org/10.2174/1871527320666210420135437 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Can Targeting the Incretin Pathway Dampen RAGE-Mediated Events in Diabetic Nephropathy?
Current Drug Targets Emerging Therapeutic Approaches Multi-Targeting Receptor Tyrosine Kinases and G Protein-Coupled Receptors in Cardiovascular Disease
Cardiovascular & Hematological Agents in Medicinal Chemistry A Novel Combined Pharmacophore Mapping and Quantitative Structure Selectivity Relationship Analysis for the Development of Potent and Selective Human Aldose Reductase Inhibitors
Current Computer-Aided Drug Design Anti-inflammatory and Immune Therapy for Alzheimers Disease: Current Status and Future Directions
Current Neuropharmacology HDL as a Target for Glycemic Control
Current Drug Targets Interrelationship Between Periapical Lesion and Systemic Metabolic Disorders
Current Pharmaceutical Design Treatment of Insulin Resistance in the Neurodegeneration
Recent Patents on CNS Drug Discovery (Discontinued) Codon Usage Biases in Alzheimers Disease and Other Neurodegenerative Diseases
Protein & Peptide Letters Emerging Risk Factors for Dementia: The Role of Blood Pressure Variability
CNS & Neurological Disorders - Drug Targets Changes in the Expression of the Alzheimers Disease-Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction
Current Alzheimer Research Cerebral Vascular Aging: Extending the Concept of Pulse Wave Encephalopathy Through Capillaries to the Cerebral Veins
Current Aging Science Overlapping the Tryptophan Catabolite (TRYCAT) and Melatoninergic Pathways in Alzheimer's Disease
Current Pharmaceutical Design Novel Approach to Cardiovascular Diseases: A Promising Probability of (Pro)Renin Receptor [(P)RR]
Current Pharmaceutical Design Pathogenesis of Stroke-Like Episodes in MELAS: Analysis of Neurovascular Cellular Mechanisms
Current Neurovascular Research Involvement of the Toxic AGEs (TAGE)-RAGE System in the Pathogenesis of Diabetic Vascular Complications: A Novel Therapeutic Strategy
Current Drug Targets Renin-Angiotensin System in Central Nervous System Diseases and its Interaction with COVID-19
Current Medicinal Chemistry Sonic Hedgehog, the Penis and Erectile Dysfunction: A Review of Sonic Hedgehog Signaling in the Penis
Current Pharmaceutical Design Gene Regulation of Aldose-, Aldehyde- and a Renal Specific Oxido Reductase (RSOR) in the Pathobiology of Diabetes Mellitus
Current Medicinal Chemistry The Effect of Sex and Gender on Diabetic Complications
Current Diabetes Reviews Metabolic Correction in the Management of Diabetic Peripheral Neuropathy: Improving Clinical Results Beyond Symptom Control
Current Clinical Pharmacology