Synthesis of Tri- and Tetra- Phenyl Substituted 1H-imidazoles in the Presence of Chitin and Pectin as Natural Catalyst

Title:Synthesis of Tri- and Tetra- Phenyl Substituted 1H-imidazoles in the Presence of Chitin and Pectin as Natural Catalyst

Volume: 10 Issue: 2

Author(s): Ghasem Marandi*, Salmeh Rasoulizadeh and Malek Taher Maghsoodlou

Affiliation:

• Chemistry Department, Faculty of Science, Urumia University, Urumia,Iran

Keywords: Chitin and pectin, benzil, aromatic aldehydes, aniline or amine, tri- and tetra- phenyl substituted 1H-imidazoles, ammonium acetate.

Abstract:

Introduction: Chitin and pectin are important natural polymers which are used as a natural catalyst for the synthesis of tri- and tetra- phenyl substituted 1H-imidazoles.

Materials and Methods: The reaction of benzil and aromatic aldehydes with ammonium acetate in the presence of chitin produces 2,4,5-triphenyl-1H-imidazoles and the reaction of benzil, aromatic aldehydes and aniline derivatives with ammonium acetate in the presence of pectin produces 1,2,4,5- tetraphenyl-1H-imidazoles, respectively.

Results: The results show that the synthesis of 2,4,5-triphenyl-1H-imidazoles and 1,2,4,5-tetraphenyl- 1H-imidazoles can be catalyzed by chitin and pectin in an effective route, respectively. All synthesized compounds are in good agreement with previously reported compounds.

Conclusion: In conclusion, an efficient methodology has been carried out to generate 2,4,5-triphenyl- 1H-imidazoles and 1,2,4,5-tetraphenyl-1H-imidazoles, by using non-toxic, cheap and in available catalysis (chitin and pectin).

Cite this article as:

Marandi Ghasem *, Rasoulizadeh Salmeh and Maghsoodlou Taher Malek , Synthesis of Tri- and Tetra- Phenyl Substituted 1H-imidazoles in the Presence of Chitin and Pectin as Natural Catalyst, Current Catalysis 2021; 10 (2) . https://dx.doi.org/10.2174/2211544710666210405094331