Cell Death in the IPLB-LdFB Insect Cell Line: Facts and Implications

Title: Cell Death in the IPLB-LdFB Insect Cell Line: Facts and Implications

Volume: 14 Issue: 2

Author(s): D. Malagoli

Affiliation:

Keywords: IPLB-LdFB insect cell line, Apoptosis, Oncosis, Autophagic cell death

Abstract: The present review summarizes findings on stress-induced cell death in the IPLB-LdFB insect cell line derived from the larval fat body of the lepidopteron Lymantria dispar. Apoptotic, oncotic and autophagic cell death have been described in these cells as a consequence of oxidative stress or ATP deprivation, and similarities between IPLB-LdFB and mammalian apoptotic pathways have been highlighted. Furthermore, starting from observations in the IPLB-LdFB cells, a link has been surmised between relevance of autophagic cell death and developmental processes in the metazoan taxa.

Cite this article as:

Malagoli D., Cell Death in the IPLB-LdFB Insect Cell Line: Facts and Implications, Current Pharmaceutical Design 2008; 14 (2) . https://dx.doi.org/10.2174/138161208783378752