Applications of the Combination of Microwave and Parallel Synthesis in Medicinal Chemistry

Title: Applications of the Combination of Microwave and Parallel Synthesis in Medicinal Chemistry

Volume: 10 Issue: 10

Author(s): Jesus Alcazar, Gaston Diels and Bruno Schoentjes

Affiliation:

Keywords: opioid receptor agonists, Piperazine Derivatives, Tropanylidene Derivatives, HIV-1 protease, malaria parasites, Obesity

Abstract: The blending of microwave heating and parallel chemistry is a logical consequence of the significant rate enhancement and higher product yield afforded by microwave technology and the increase in productivity afforded by combinatorial chemistry. For this reason, this combination has become increasingly popular in the organic chemistry community. The current review highlights the application of this approach as a way to increase the rate of analogue synthesis in medicinal chemistry.

Cite this article as:

Alcazar Jesus, Diels Gaston and Schoentjes Bruno, Applications of the Combination of Microwave and Parallel Synthesis in Medicinal Chemistry, Combinatorial Chemistry & High Throughput Screening 2007; 10 (10) . https://dx.doi.org/10.2174/138620707783220383