Abstract
Coumarin is a heterocyclic scaffold and its derivatives, namely Schiff bases, esters, and hydrazides, etc., play an important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological activities like antifungal, antimicrobial, antiviral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, antiaflatoxigenic, analgesics, antioxidant and Oestrogenic, etc., have been analyzed. This review covers the latest literature and knowledge on the synthetic procedures for various coumarin and its derivatives, their biological and pharmacological applications.
Keywords: Coumarin, Synthesis, derivatives, Biological activities, heterocyclic compounds, benzo-β-pyrone.
Graphical Abstract
Letters in Organic Chemistry
Title:Overview of Coumarins and its Derivatives: Synthesis and Biological Activity
Volume: 18 Issue: 11
Author(s): Tanvi Sahni, Sunita Sharma*, Diksha Verma and Pardeep Kaur
Affiliation:
- Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana,India
Keywords: Coumarin, Synthesis, derivatives, Biological activities, heterocyclic compounds, benzo-β-pyrone.
Abstract: Coumarin is a heterocyclic scaffold and its derivatives, namely Schiff bases, esters, and hydrazides, etc., play an important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological activities like antifungal, antimicrobial, antiviral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, antiaflatoxigenic, analgesics, antioxidant and Oestrogenic, etc., have been analyzed. This review covers the latest literature and knowledge on the synthetic procedures for various coumarin and its derivatives, their biological and pharmacological applications.
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Cite this article as:
Sahni Tanvi , Sharma Sunita *, Verma Diksha and Kaur Pardeep , Overview of Coumarins and its Derivatives: Synthesis and Biological Activity, Letters in Organic Chemistry 2021; 18 (11) . https://dx.doi.org/10.2174/1570178617999201006195742
DOI https://dx.doi.org/10.2174/1570178617999201006195742 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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