Molecular Hydrogen Application in Stroke: Bench to Bedside

Title:Molecular Hydrogen Application in Stroke: Bench to Bedside

Volume: 27 Issue: 5

Author(s): Lei Huang, Cameron Lenahan, Warren Boling, Jiping Tang and John H. Zhang*

Affiliation:

• Department of Neurosurgery, Loma Linda University, Loma Linda, CA92354,United States

Keywords: Ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, hydrogen gas, hydrogen-rich saline, hydrogen-rich water, antioxidant, neuroprotection.

Abstract: Stroke is a major cause of mortality and morbidity worldwide. Effective treatments are limited. Molecular hydrogen is emerging as a novel medical gas with therapeutic potential for various neurological diseases, including stroke. We reviewed the experimental and clinical findings of the effects of molecular hydrogen therapy in stroke patients and models. The underlying neuroprotective mechanisms against stroke pathology were also discussed.

Cite this article as:

Huang Lei , Lenahan Cameron , Boling Warren, Tang Jiping and Zhang H. John *, Molecular Hydrogen Application in Stroke: Bench to Bedside, Current Pharmaceutical Design 2021; 27 (5) . https://dx.doi.org/10.2174/1381612826666200917152316