Melatonin Could Be Beneficial in SARS-CoV-2 Therapy

Title:Melatonin Could Be Beneficial in SARS-CoV-2 Therapy

Volume: 11 Issue: 5

Author(s): Sanaz Baghban Rahimi and Ahmad Hosseinzadeh Adli*

Affiliation:

• Department of Microbiology, Tabriz University of Medical Sciences, Tabriz,Iran

Keywords: Melatonin, SARS-CoV-2, treatment, anti-inflammatory, immunomodulator, natural.

Abstract: Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological conditions in the body, such as immune modulation, anti-inflammation, and antioxidant. Melatonin is found in foods, animal and human milk and increases the expression of anti-inflammatory cytokines and, as an adjuvant treatment in SARS-- CoV-2 infection, it may have considerable therapeutic potential, because of its safety and immunomodulatory effects.

Cite this article as:

Rahimi Baghban Sanaz and Adli Hosseinzadeh Ahmad*, Melatonin Could Be Beneficial in SARS-CoV-2 Therapy, The Natural Products Journal 2021; 11 (5) . https://dx.doi.org/10.2174/2210315510999200905130902