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Mini-Review Article

阴道炎：耐药性回顾

卷 21, 期 16, 2020

页: [1672 - 1686] 页: 15

弟呕挨: 10.2174/1389450121666200804112340

价格: $65

摘要

女性生殖道感染在不同年龄段的人群中发病率很高，对公共卫生产生重要影响。其中，阴道炎是指由于引起毛滴虫病，细菌性阴道病和念珠菌性念珠菌病的病原体的存在而引起的外阴和/或阴道炎症。这些感染，怀孕并发症以及艾滋病毒的传播和获取的便利都与一些不适有关。微生物对用于治疗的药物的抵抗力日益显着，因为妇女报告这些感染和相关合并症复发。在这篇综述中讨论了针对阴道毛滴虫，念珠菌和阴道加德纳菌的治疗中的药物的不同耐药机制，以及与发病机理和治疗有关的方面。这项研究旨在为药物设计做出贡献，避免由于耐药性导致治疗无效。有效治疗阴道炎的替代疗法将减少感染的复发，并因此减少卫生系统产生的高昂费用，从而改善妇女的福祉。

关键词: 阴道炎，药物靶向，耐药性，阴道毛滴虫，阴道加德纳菌，假丝酵母。

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