摘要
基于光敏剂(PS)在光照射下诱导的光化学反应,光动力疗法(PDT)是一种有希望的恶性肿瘤替代疗法。 最近的研究表明,PDT导致外泌体从肿瘤组织中大量释放。 众所周知,作为载体的外泌体通过转运多种生物活性分子(例如脂质,蛋白质,mRNA,miRNA和lncRNA)在细胞间通信中起着重要作用。 因此,探索外泌体在光动力抗癌治疗中的作用已引起广泛关注。 在本文中,我们将简要介绍PDT和外泌体的基本原理,并重点讨论外泌体在光动力抗癌治疗中的作用,以进一步丰富和促进PDT的发展。
关键词: 光动力疗法,肿瘤,外泌体,肿瘤微环境,肿瘤转移,肿瘤耐药性。
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