The article by Dr. Martin L. Pall is published in the
journal, Current Alzheimer Research, 2022
NEWS RELEASE 25-APR-2022
For almost a quarter of a
century, researchers have been studying and publishing on the effect of calcium
on Alzheimer’s Disease. Research has led to the development of the calcium
hypothesis of Alzheimer’s disease, which argues that Alzheimer’s is caused by
excessive intracellular calcium.
Calcium causes changes to the
brain
Calcium build-up in cells results
in diverse range of changes in the brain. There are two significant changes
that develop conditions for Alzheimer’s disease.
EMFs and Calcium build up
Pulsed electronically generated
electromagnetic fields (EMFs) used for wireless communication are coherent
producing strong electric and magnetic forces that act in the cells of our
bodies primarily via activation of
voltage-gated calcium channels (VGCCs). VGCC activation produces rapid
increases in intracellular calcium levels. Therefore, EMF exposures
produce changes with lead to excessive intracellular calcium. This buildup explains
the effects on the brain in Alzheimer’s disease.
These EMF induced changes to
intracellular calcium levels have been demonstrated in animal models of
Alzheimer’s disease. Research has shown the involvement of two pathways that
lead to Alzheimer’s disease. Each of the two pathways producing
pathophysiological effects following EMF exposure are important in Alzheimer’s
causation: the excessive calcium signaling pathway and the
peroxynitrite/oxidative stress/inflammation pathway.
Professor Martin L. Pall, at the
Washington State University has been studying this phenomenon for a decade.
“EMFs act via peak electric and time varying magnetic forces at a nanosecond
time scale.”, says Professor Pall. Such peaks are vastly increased with each
increase in pulse modulation produced by smarter cell phones, smart meters,
smart cities and radar in self driving vehicles. “Any of these may produce the
ultimate nightmare – extremely early onset Alzheimer’s Disease.”
These findings provide powerful
evidence that EMFs can cause Alzheimer’s disease. Human and animal studies add
still more evidence to the calcium hypothesis of Alzheimer’s disease.
A look at some more evidence
Professor Pall summarizes the
evidence in a recent review in Current Alzheimer Research.
Human genetic and pharmacological
studies show that elevated VGCC activity causes increased Alzheimer’s
incidence. Consequently, it is not just calcium that is important. VGCC
activity, which is directly greatly increased by EMF exposure, is also
important in causing Alzheimer’s.
12 recent occupational exposure
assessments have found that people having occupational EMF exposures have
higher Alzheimer’s incidence. Some studies suggest that EMFs shorten the
normal 25-year latency period of Alzheimer’s disease.
Earlier occupational exposure
studies (in the 1970s and 1980s) showed that neurological / neuropsychiatric
reported effects, associated with EMF exposures, developed cumulatively, such
that longer times of exposure to the same EMFs, produced more severe effects. This
parallels cumulative effects in neurodegeneration.
The age of onset of Alzheimer’s
has decreased over the past 20 years or so, with the timing corresponding to
the large recent increases in wireless communication EMF exposures.
Recent studies report age 30 to 40 Alzheimer’s cases.
Very young people who are exposed
to cell phone or Wi-Fi radiation for many hours per day may develop digital
dementia.
El-Swefy et
al, in 2008, showed that 2 hours per day very low intensity mobile
phone base station (cell phone tower) radiation produced massive
neurodegeneration of the brains of young rats. 34% of the brain cells
died in 4 weeks. 11 measured brain changes and 4 observed behavioral
changes were each greatly lowered by the VGCC calcium channel blocker amlodipine.
These findings show is that EMFs most of us are exposed to every day,
acted via VGCC activation to produce universal massive,
extraordinarily rapid neurodegeneration in young rats. The researchers
did not examine any Alzheimer’s specific brain changes.
However, Jiang et
al. (2013 & 2016) looked at EMF pulses in rats found
Alzheimer’s specific changes but also some less specific changes in the
hippocampus, a brain region which is heavily impacted in Alzheimer’s. Jiang
2013 exposed rats to a series of EMF pulses in one day to 2-month old rats,
finding apparent universal Alzheimer’s effects in 20 month old rats (roughly
the equivalent of 42-year-old humans coming down with near universal
Alzheimer’s). The 2016 paper exposed the rats to EMF pulses once a day,
causing Alzheimer’s at 10 months of age (similar to 21-year-old people with
extremely early onset Alzheimer’s). Both El-Swefy and Jiang found massive
neurodegeneration in young rats simply from exposing them to EMF pulses.
What needs to be done?
Three types of studies are
urgently needed to be performed by independent scientists:
1. Brain marker surveys of
Alzheimer’s disease and MRI brain scans for abnormalities among young people
who show signs of digital dementia.
2. EMF exposures assessments for
pre-diagnosis environments for people aged 30 to 40 who have been diagnosed
with early onset Alzheimer’s disease. These assessments should compare phone
and cell phone tower radiation, Wi-Fi radiation, smart meter and dirty
electricity radiation levels with normal controls.
3. Examinations for early signs
of Alzheimer’s disease among people living near small cell antennae for a year
or more.
“Findings from each of these
studies should be shared with the general public”, says Professor Pall, “so
that everyone can take the steps necessary to reduce the incidence of early
onset Alzheimer’s disease.”
Read the published article
here: https://www.eurekaselect.com/article/120618
Current Alzheimer Research
10.2174/1567205019666220202114510
Low intensity electromagnetic fields act via
voltage-gated calcium channel (VGCC) activation to cause very early onset
Alzheimer’s disease: 18 distinct types of evidence
11-Mar-2022
