This book summarizes the cutting-edge experimental research on heterocyclic compounds used as anti-inflammatory agents in ten chapters. Each chapter is authored by experts in medicinal chemistry and is supplemented with scientific references for advanced reading. The book covers several types of heterocyclic compounds and their derivatives including : - pyrimidine and pyrimidinone derivatives - 1,2,3, and 1,2,4 triazoles - imidazole and benzimidazole derivatives - oxazole, oxadiazole, isoxazoline, and oxazoline derivatives - thiazole and thiazolidinone derivatives - pyrazole and pyrazoline - Carbazoles and their derivatives - azipines, quinolines, and coumarins This is a timely reference for medicinal chemists interested in developing new heterocycles for anti-inflammatory drugs. Contributors have discussed the effects of these compounds on different types of inflammation and their evolution in drug development as therapeutic agents to give a wider perspective to readers.

This reference provides an update on current therapies to treat neglected diseases, a class of diseases that primarily affect tropical regions where investment in research and development is limited. The book starts with an introduction to neglected diseases followed by reviews of therapeutic strategies to overcome the impact of neglected diseases. This is followed by updated information for handling leprosy, dengue, lymphatic filariasis, dracunculiasis, helminthiasis, Chagas’ disease, neurocysticercosis, leishmaniasis, rabies, trematodiasis, buruli ulcer and trachoma in 10 focused chapters, respectively. The chapters provide information on disease mechanism, transmission and management protocols, along with scientific references. The book serves as a resource for healthcare professionals, and scholars who need a detailed understanding of these infectious diseases.

Lifestyle diseases and related conditions present a major healthcare challenge for children, posing a significant threat to their well-being. The Editors have compiled chapters to present a multicentric approach to the subject. This book is an insightful reference on lifestyle diseases and its management in adolescents. It includes twelve topics with a focus on physical, emotional and behavioral aspects of lifestyle diseases. Starting with an introduction to lifestyle issues that can manifest into disease states, the book progresses to advanced topics, including emotional and cognitive developments, effects of mass media ranging from emotional and cognitive health, nutrition requirements and eating disorders, physical inactivity, eating and sleeping patterns, drug and alcohol-abuse, social behavior, anxiety and mental health. The book highlights the risk factors and determinants of these diseases, and where an immediate intervention is needed. An updated understanding of the diseases with scientific references gives readers crucial information for setting the groundwork for long-term public health policy formulation. This book serves as a primary resource for scholars and trainees in nursing, medical (pediatrics and endocrinologists) and paramedical courses who are required to understand lifestyle diseases with a focus on adolescents. Readers and professionals in public health, life-sciences and related disciplines can also use this as a secondary reference.

Lifestyle diseases and related conditions present a major healthcare challenge for children, posing a significant threat to their well-being. The Editors have compiled chapters to present a multicentric approach to the subject. This book is an insightful reference on lifestyle diseases and its management in adolescents. It includes ten chapters with a focus on systemic disorders that are linked to lifestyle issues. Topics in this volume include gut microbiome and gastrointestinal disorders, neurological disorders, dental diseases, respiratory diseases and allergies associated with pesticides, cancer, hypertension, cardiovascular disorders, diabetes, polycystic ovarian syndrome, and common infectious diseases. The book highlights the risk factors and determinants of these diseases, and where an immediate intervention is needed. An updated understanding of the diseases with scientific references gives readers crucial information for setting the groundwork for long-term public health policy formulation. This book serves as a primary resource for scholars and trainees in nursing, medical (pediatrics and endocrinology) and paramedical courses who are required to understand lifestyle diseases with a focus on adolescents. Readers and professionals in public health, life-sciences and related disciplines can also use this as a secondary reference.

Advances in Diagnostics and Immunotherapeutics for Neurodegenerative Diseases delves into the intricate mechanisms underlying neurodegenerative disorders and highlights cutting-edge diagnostic methods and innovative immunotherapeutic strategies. This comprehensive book addresses several key themes crucial to understanding and combating these debilitating conditions with an updated understanding of neurodegenerative disorders and a review of the latest advancements in diagnostic and treatment strategies. Key Themes Neuroinflammation: examines the complex molecular pathways involved in neuroinflammatory responses and their impact on disease dynamics. Gut-Brain Axis: A thorough discussion on the relationship between the gut microbiome and neurodegenerative processes is presented. Advanced Diagnostics: A state-of-the-art review of diagnostic techniques provides updates on advanced neuroimaging modalities, cerebrospinal fluid biomarker analysis, and genetic testing. Epigenetic Regulation of Microglia: Covers the emerging field of epigenetic modifications and their role in modulating microglial activation and function. Immunotherapeutics: Learn about the potential of monoclonal antibodies, immune modulators, and repurposed drug therapies in slowing disease progression and improving patient outcomes. This book serves as a valuable resource for researchers, clinicians, and students in the fields of molecular biology, neuroimmunology, and clinical neurology.

Herbal Medicine: Back to the Future compiles expert reviews on the application of herbal medicines (including Ayurveda, Chinese traditional medicines and alternative therapies) to treat different ailments. The book series demonstrates the use of sophisticated methods to understand traditional medicine, while providing readers a glimpse into the future of herbal medicine. This volume presents reviews of plant based therapies useful for treating different infectious diseases. The reviews highlight different sources of antiviral, antibacterial and antifungal herbs. The volume concludes with a review on the therapeutic potential of herbs for treating rheumatoid arthritis. The chapters included in this volume are as follows: - Brazilian Siparuna species as a Source of antiviral agents - Antimicrobial and antifungal potential of Indian spices - Role of herbal medicines in the treatment of infectious diseases - Herbal medicine: traditional approach to treat infectious diseases - Exploring the therapeutic potential of medicinal plants for rheumatoid arthritis This volume is essential reading for all researchers in the field of natural product chemistry and pharmacology. Medical professionals involved in internal medicine who seek to improve their knowledge about herbal medicine and alternative therapies for tropical and other infectious diseases will also benefit from the contents of the volume.

Neuroendoscopy and Interventional Pain Medicine is a clinically focused medical monograph series. With contributions from a team of internationally recognized neurosurgeons and spinal surgery specialists, the series aims to illuminate the latest advancements in minimally invasive neurosurgical techniques and pain management. Each volume offers invaluable insights into the future of minimally invasive treatments in this medical subspecialty. Interventional Pain Surgery is the third of the monograph series. This book comprehensively covers endoscopic techniques for spinal surgery. Topics include interlaminar lumbar endoscopy, transforaminal lumbar discectomy, endoscopic approaches for lumbar spinal canal stenosis, and management of chronic low back pain through rhizotomy and rhiziolysis. The endoscopic treatment of basivertebral neuropathy, cervical foraminotomy, and decompression techniques is explained in dedicated chapters. Finally, the book also addresses endoscopic posterior lumbar interbody fusion and procedures for adjacent segment disease after lumbar fusion. Key Features - Covers a wide range of topics in neuroendoscopy and interventional pain medicine - Emphasizes evidence-based approaches to treatment - Offers clinical perspectives from expert surgeons - Includes scientific references for researchers and advanced learners It is an essential resource for readers who need to enhance their understanding of the latest technological advancements in neuroendoscopy and interventional pain medicine and apply these innovative techniques to improve patient outcomes.

Textbook of Advanced Dermatology: Pearls for Academia and Skin Clinics is an essential reference for practicing dermatologists in hospitals and clinics. The book aims to provide interesting tips which cannot be found in traditional dermatology handbooks. The contributors include top minds in dermatology and related fields such as Joe Niamtu, Samuel Lam, and Steven Feldman. Topics in the book include novel, original formulations for topical compounds, ways to improve patient adherence to prescriptions, business tips, novelties in skin surgery, and solutions for preventing patient complaints and legal suits. The book also highlights the authors personal experiences gained over many years in improving everyday clinical dermatology practice. The book is divided into 5 sections each representing pearls of advice: Teaching Pearls, Medical Pearls, Publication Pearls, Procedural Pearls, and Business Pearls, encompassing all of the broad realm of dermatology.

Neuroendoscopy and Interventional Pain Medicine is a clinically focused medical monograph series. With contributions from a team of internationally recognized neurosurgeons and spinal surgery specialists, the series aims to illuminate the latest advancements in minimally invasive neurosurgical techniques and pain management. Each volume offers invaluable insights into the future of minimally invasive treatments in this medical subspecialty. Endoscopy and Fetoscopy Techniques for the Brain and Neuroaxis is the second of the monograph series. The book covers advanced endoscopic techniques for brain and spinal surgeries. Topics include visualization of the brain, endoscopic approaches to the sellar region, fetoscopy treatments for myelomeningocele, and methods for cancer pain relief. It also discusses endoscopic correction of craniosynostosis in children, complications like autonomic dysreflexia, and the importance of identifying the Adamkiewicz system in spinal procedures. Key Features - Covers a wide range of topics in neuroendoscopy and interventional pain medicine - Emphasizes evidence-based approaches to treatment - Offers clinical perspectives from expert surgeons - Includes scientific references for researchers and advanced learners It is an essential resource for readers who need to enhance their understanding of the latest technological advancements in neuroendoscopy and interventional pain medicine and apply these innovative techniques to improve patient outcomes.

Neuroendoscopy and Interventional Pain Medicine is a clinically focused medical monograph series. With contributions from a team of internationally recognized neurosurgeons and spinal surgery specialists, the series aims to illuminate the latest advancements in minimally invasive neurosurgical techniques and pain management. Each volume offers invaluable insights into the future of minimally invasive treatments in this medical subspecialty. Interventional Pain Surgery is the third of the monograph series. This book comprehensively covers endoscopic techniques for spinal surgery. Topics include interlaminar lumbar endoscopy, transforaminal lumbar discectomy, endoscopic approaches for lumbar spinal canal stenosis, and management of chronic low back pain through rhizotomy and rhiziolysis. The endoscopic treatment of basivertebral neuropathy, cervical foraminotomy, and decompression techniques is explained in dedicated chapters. Finally, the book also addresses endoscopic posterior lumbar interbody fusion and procedures for adjacent segment disease after lumbar fusion. Key Features - Covers a wide range of topics in neuroendoscopy and interventional pain medicine - Emphasizes evidence-based approaches to treatment - Offers clinical perspectives from expert surgeons - Includes scientific references for researchers and advanced learners It is an essential resource for readers who need to enhance their understanding of the latest technological advancements in neuroendoscopy and interventional pain medicine and apply these innovative techniques to improve patient outcomes.