Frontiers in Clinical Drug Research : Anti - infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The eighth volume of this series presents comprehensive reviews of interest to readers interested in the treatment of inflammatory diseases, new antiviral agents and strategies, specific antiprotozoal drugs that work against leishmania and helminths, and a study on potential agents against American foulbrood in honey bees. The 7 reviews included in this volume are: - Monoclonal antibodies as therapeutic agents for inflammatory diseases - Pharmacotherapy of emerging antiviral agents - Antiviral activity of vitamin D and COVID-19: current understanding - Anti-infectives to combat leishmaniasis - Anthelmintic drug discovery: current situation and future perspectives - Therapeutic targets for emerging Zika virus infection and vaccines in clinical trials - Agro-industrial waste: new source of raw material for the control of American foulbrood in honey bees

Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The first volume of this series features 7 chapters that cover a variety of topics including: -Antiretroviral drug development -HIV-1 genomics -HIV drug targets such as ribosomes and HIV Integrase -HAART associated nephrotoxicity

Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The second volume of this series features 5 chapters that cover a variety of topics including: - HIV-1 Integrase Inhibitors - HIV in vaginal mucosa - Long-Acting Antiretroviral Formulations -The world of people living with HIV/AIDS

Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The third volume of this series features 5 chapters that cover a variety of topics including: - Studies of HPV infections in HIV positive people - Allosteric Integrase Inhibitors - HAART - Drugs targeting various types HIV-1 enzymes

Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. </p> <p> The fourth volume of this series features 5 chapters that cover these topics: </p> <p> - Design and Synthesis of HIV-1 Protease Inhibitors </p> <p> - Potential Magnetic Nanotherapeutics for Management of neuroAIDS </p> <p> - Syntheses of FDA Approved Integrase Inhibitor HIV Drugs and Improved Manufacturing using Flow Processing </p> <p> - The Development and Clinical Progress on Chemokine Receptor-Based HIV Entry Inhibitors </p> <p> - Sexually Transmitted Co-infections in Persons Living with HIV </p>

Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The fifth volume of this series features 5 chapters that cover these topics: - Clinical Eradication of Latent HIV Reservoirs: Where Are We Now? - HIV-1 Genotypic Drug Resistance Testing and Next-Generation Sequencing - Current and Promising Multiclass Drug Regimens and Long-Acting Formulation Drugs in HIV Therapy - Role of Nanotechnology in HIV Diagnosis and Prognosis - Preventive and Therapeutic Features of Combination Therapy for HIV

Histopathological Diagnosis of Leprosy, is a comprehensive guide to the medical pathology of Hansen’s disease, which is a complex and clinically challenging infection caused by Mycobacterium leprae. Readers will find 8 chapters on key topics on the subject including general aspects of leprosy, different forms of leprosy (polar, borderline, etc.), reaction types and complications. The information presented in the handbook will equip the reader with the knowledge required to identify the disease in patients and perform differential diagnosis where required. Key Features: - 8 chapters dedicated to key topics about leprosy and its diagnosis - More than 2014 figures featuring over 1000 clinical and histopathological photographs - Complete information about differential diagnosis and reaction phenomena - includes a section dedicated to special and complicated cases - References for further reading - Brings the expertise of renowned physicians to the reader The detailed presentation of the book is of great value to both healthcare professionals (pathologists, dermatologists, physicians) who are involved in the care of leprosy patients, and medical residents who are seeking information about the disease as part of their medical training.

Human papillomavirus (HPV) infection is one of the most frequently sexually transmitted diseases in the world. HPV infections are responsible for almost all cases of genital warts and are also responsible for multiple cancer in different regions of the body. Several studies on HPV diagnosis and vaccine development are in progress. Recently, two commercial vaccines such as Gardasil and Cervarix have been used to prevent HPV infections. Various drugs have also been tested in clinical trials for the treatment of HPV-related cancers. HPV infections: Diagnosis, Prevention, and Treatment provides a comprehensive overview of diagnosis, prevention and treatment in HPV-related infections. Chapters cover a large range of topics including HPV epidemiology, molecular biology, transmission, diagnosis, prevention, and treatment along with information about preclinical and clinical experiments. This book is intended as a comprehensive handbook for medical students and residents who require information about HPV and the treatment of HPV related diseases.

Influenza is one of the most ancient and intriguing diseases that has been accompanying our civilization for millennia. While mankind has successfully defeated many dangerous influenza infections in the last couple of centuries, influenza control remains a serious problem for public health. A number of influenza vaccines and antiviral compounds have been licensed in recent times. However, the influenza virus is still ahead of us, as it continues to persistently infect humans to this day. Influenza: A Century of Research shows how influenza virology has developed historically and the tremendous knowledge that has been uncovered in the study of influenza. In this monograph, the authors present a historical perspective on influenza, chronologically, with an emphasis on its virology. Chapters cover information about the isolation of the first influenza viruses, substrates, and models for studying influenza, structure, and life cycle of the influenza virus, mechanisms of attenuation and virulence. Chapters progress into the multidisciplinary aspects of influenza research such as influenza virus ecology and the evolutionary origin of epidemic and pandemic influenza viruses. A significant part of the book also covers the description of the prevention and treatment of influenza and reasons that have contributed to insufficient control for influenza. The questions of how the COVID-19 pandemic affects the circulation of seasonal respiratory viruses, and if we can eliminate this virus are also addressed. Influenza: A Century of Research is an informative source of information for a broad range of readers, academic or otherwise, who are interested in knowing more about the disease.