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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Editorial

Catalysis and the Synthesis of Pharmacologically Small Molecules

Author(s): Mohammad A. Alam

Volume 23, Issue 9, 2019

Page: [976 - 977] Pages: 2

DOI: 10.2174/138527282309190710102427

[1]
Roberts, S.M.; Gibb, A.J. Chapter 1 - Introduction to enzymes, receptors and the action of small molecule drugs.In Introduction to Biological and Small Molecule Drug Research and Development; Ganellin, R.; Roberts, S.; Jefferis, R., Eds.; Elsevier: Oxford, 2013, pp. 1-55.
[2]
Allison, D.; Delancey, E.; Ramey, H.; Williams, C.; Alsharif, Z.A.; Al-khattabi, H.; Ontko, A.; Gilmore, D.; Alam, M.A. Synthesis and antimicrobial studies of novel derivatives of 4-(4-formyl-3-phenyl-1H-pyrazol-1-yl)benzoic acid as potent anti-Acinetobacter baumannii agents. Bioorg. Med. Chem. Lett., 2017, 27, 387-392.
[3]
Zakeyah, A.A.; Whitt, J.; Duke, C.; Gilmore, D.F.; Meeker, D.G.; Smeltzer, M.S.; Alam, M.A. Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid. Bioorg. Med. Chem. Lett., 2018, 28, 2914-2919.
[4]
Whitt, J.; Duke, C.; Sumlin, A.; Chambers, S.A.; Alnufaie, R.; Gilmore, D.; Fite, T.; Basnakian, A.G.; Alam, M.A. Synthesis of Hydrazone Derivatives of 4-[4-Formyl-3-(2-oxochromen-3-yl)pyrazol-1-yl]benzoic acid as Potent Growth Inhibitors of Antibiotic-resistant Staphylococcus aureus and Acinetobacter baumannii. Molecules, 2019, 24, 2051.
[5]
Okolo, C.; Ali, M.A.; Newman, M.; Chambers, S.A.; Whitt, J.; Alsharif, Z.A.; Day, V.W.; Alam, M.A. Hexafluoroisopropanol-Mediated Domino Reaction for the Synthesis of Thiazolo-androstenones: Potent Anticancer Agents. ACS Omega, 2018, 3, 17991-18001.
[6]
Ali, M.A.; Okolo, C.; Alsharif, Z.A.; Whitt, J.; Chambers, S.A.; Varma, R.S.; Alam, M.A. Benign Synthesis of Thiazolo-androstenone Derivatives as Potent Anticancer Agents. Org. Lett., 2018, 20, 5927-5932.
[7]
Alam, M.A.; Reddy, Y.S.; Ali, M.A. New and under explored epigenetic modulators in search of new paradigms. Medicinal chemistry (Shariqah (United Arab Emirates)), 2015, 11, 271-285.
[8]
Mohammad, A.A. Methods for Hydroxamic Acid Synthesis. Curr. Org. Chem., 2019, 23, 976-991.
[9]
Gurrapu, S.; Jonnalagadda, S.K.; Alam, M.A.; Ronayne, C.T.; Nelson, G.L.; Solano, L.N.; Lueth, E.A.; Drewes, L.R.; Mereddy, V.R. Coumarin carboxylic acids as monocarboxylate transporter 1 inhibitors: In vitro and in vivo studies as potential anticancer agents. Bioorg. Med. Chem. Lett., 2016, 26, 3282-3286.
[10]
Saigal; Sumbulunnisan, S.; Habibur, R.; Md. Musawwer, K., Aminocoumarins: A Privileged Precursor for the Synthesis of Fused Heterocycles. Curr. Org. Chem., 2019, 23, 1043-1073.
[11]
Ludwig, J.R.; Schindler, C.S. Catalyst: Sustainable Catalysis. Chem, 2017, 2, 313-316.
[12]
Cabrele, C.; Reiser, O. The Modern Face of Synthetic Heterocyclic Chemistry. J. Org. Chem., 2016, 81, 10109-10125.
[13]
Alsharif, Z.A.; Alam, M.A. Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol. RSC Advances, 2017, 7, 32647-32651.
[14]
Alam, M.A.; Alsharif, Z.; Alkhattabi, H.; Jones, D.; Delancey, E.; Gottsponer, A.; Yang, T. Hexafluoroisopropyl alcohol mediated synthesis of 2,3-dihydro-4H-pyrido[1,2-a]pyrimidin-4-ones. Sci. Rep., 2016, 6, 36316.
[15]
Alsharif, Z.; Ali, M.A.; Alkhattabi, H.; Jones, D.; Delancey, E.; Ravikumar, P.C.; Alam, M.A. Hexafluoroisopropanol mediated benign synthesis of 2H-pyrido[1,2-a]pyrimidin-2-ones by using a domino protocol. New J. Chem., 2017, 41, 14862-14870.
[16]
Arun, V.; Suman De, S. Recent Developments in the de Novo Synthesis of Heterocycles by First-Row Transition-Metal-Catalyzed Acceptorless Dehydrogenation. Curr. Org. Chem., 2019, 23, 1003-1016.
[17]
John, C.H. Recent Advances in Palladium-Catalyzed Oxidative Cyclizations. Curr. Org. Chem., 2019, 23, 1017-1042.
[18]
Tokeer, A.; Ruby, P.; Huma, K. Iron Oxide Nanoparticles: An Efficient Nano-catalyst. Curr. Org. Chem., 2019, 23, 992-1002.

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