摘要
珊瑚来源的微生物以其产生具有药物重要性的新产品的固有能力而闻名。 到2014年,已从珊瑚来源的微生物中分离出近260种海洋天然产物(MNP)。在过去三年中,从珊瑚相关的微生物中分离出118种MNP,包括46种新化合物,两种具有新颖骨架的化合物和四种新型天然物质。 产品。 它们中的大多数表现出针对肿瘤细胞系,寄生虫,病原细菌,真菌和病毒的体外或体内活性。 我们回顾了2015年至2017年报告的天然产物,它们具有针对不同生物学目标的广泛生物活性。
关键词: 珊瑚来源的微生物,海洋天然产物,生物活性,药物潜力,寄生虫,致病菌。
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