Abstract
Applications of Acceptorless Dehydrogenation (AD) process for the synthesis of important heterocycles are discussed. The key features of AD process are the generation of more reactive carbonyl/imine compounds from alcohols/amines by the release of dihydrogen as a stoichiometric byproduct. In this review, we document recent advances in this field by using first row transition metal catalysts and easily accessible coupling partners, thus offering cost-effective access to different heterocyclic rings.
Keywords: Hydrogen transfer, alcohols, transition-metal, dehydrogenation, heterocycles, acceptorless dehydrogenation.
Graphical Abstract
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Call for Papers in Thematic Issues
31 December, 2024
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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