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Current Bioinformatics

Editor-in-Chief

ISSN (Print): 1574-8936
ISSN (Online): 2212-392X

General Research Article

MoABank: An Integrated Database for Drug Mode of Action Knowledge

Author(s): Yu-di Liao and Zhen-ran Jiang*

Volume 14, Issue 5, 2019

Page: [446 - 449] Pages: 4

DOI: 10.2174/1574893614666190416151344

Price: $65

Abstract

Background: With the declining trend of new drugs yield each year, more comprehensive knowledge of drug MoAs can help identify new applications of available drugs and discovery novel mechanism of drug action.

Objective: Therefore, construction of a specialized drug mode of action (MoA) database is of paramount importance for new drug research & development.

Methods: This paper introduces an integrated database for drug mode of action knowledge (MoABank).

Results: This database can provide the knowledge about drug MoAs, targets, pathways, side effects and other drug-related information for researchers.

Conclusion: We believe MoABank can make it more convenient for users to obtain the drug MoA information in the future.

Keywords: Information integration, MoA, database, drug molecular, cheminformatics, bioactivity data.

Graphical Abstract

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