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Current Nanoscience

Editor-in-Chief

ISSN (Print): 1573-4137
ISSN (Online): 1875-6786

Perspective

Cucurbit[n]urils in Drug Delivery and Biomedical Systems

Author(s): Feng Liang and Wenshuo Yang

Volume 15, Issue 4, 2019

Page: [326 - 327] Pages: 2

DOI: 10.2174/157341371504190301101927

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[2]
Ghosh, I.; Nau, W.M. The strategic use of supramolecular pKa shifts to enhance the bioavailability of drugs. Adv. Drug Deliv. Rev., 2012, 64, 764-783.
[3]
Wang, L.; Li, L.; Fan, Y.; Wang, H. Host-guest supramolecular nanosystems for cancer diagnostics and therapeutics. Adv. Mater., 2013, 25, 3888-3898.
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Ma, X.; Zhao, Y. Biomedical applications of supramolecular systems based on host-guest interactions. Chem. Rev., 2015, 115, 7794-7839.
[5]
Barrow, S.J.; Kasera, S.; Rowland, M.J.; del Barrio, J.; Scherman, O.A. Cucurbituril-based molecular recognition. Chem. Rev., 2015, 115, 12320-12406.
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Bai, H.; Lv, F.; Liu, L.; Wang, S. Supramolecular antibiotic switches: Apotential strategy for combating drug resistance. Chem. Eur. J, 2016, 22, 11114-11121.
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Yang, Y.; He, P.; Wang, Y.; Bai, H.; Wang, S.; Xu, J.F.; Zhang, X. Supramolecular radical anions triggered by bacteria in situ for selective photothermaltherapy. Angew. Chem. Int. Ed., 2017, 56, 16239-16242.
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Li, S.; Jiang, N.; Zhao, W.; Ding, Y.; Zheng, Y.; Wang, L.; Zheng, J.; Wang, R. An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine. Chem. Commun., 2017, 53, 5870-5873.
[9]
Tian, T.; Song, Y.; Wei, L.; Wang, J.; Fu, B.; He, Z.; Yang, X.; Wu, F.; Xu, G.; Liu, S.; Li, C.; Wang, S.; Zhou, X. Reversible manipulation of the G-quadruplex structures and enzymatic reactions through supramolecular host–guest interactions. Nucleic Acids Res., 2017, 45, 2283-2293.
[10]
Tonga, G.Y.; Jeong, Y.; Duncan, B.; Mizuhara, T.; Mout, R.; Das, R.; Kim, S.T.; Yeh, Y-C.; Yan, B.; Hou, S.; Rotello, V.M. Supramolecular regulation of bioorthogonal catalysis in cells using nanoparticle-embedded transition metal catalysts. Nat. Chem., 2015, 7, 597-603.
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Le, N.D.B.; Yesilbag Tonga, G.; Mout, R.; Kim, S-T.; Wille, M.E.; Rana, S.; Dunphy, K.A.; Jerry, D.J.; Yazdani, M.; Ramanathan, R.; Rotello, C.M.; Rotello, V.M. Cancer cell discrimination using host-guest “doubled” arrays. J. Am. Chem. Soc., 2017, 139, 8008-8012.
[12]
Bosmans, R.P.G.; Briels, J.M.; Milroy, L-G.; de Greef, T.F.A.; Merkx, M.; Brunsveld, L. Supramolecular control over split-luciferase complementation. Angew. Chem. Int. Ed., 2016, 55, 8899-8903.
[13]
de Vink, P.J.; Briels, J.M.; Schrader, T.; Milroy, L-G.; Brunsveld, L.; Ottmann, C. A binary bivalent supramolecular assembly platform based on cucurbit[8]uril and dimeric adapter protein 14-3-3. Angew. Chem. Int. Ed., 2017, 56, 8998-9002.
[14]
Wang, S.R.; Song, Y.Y.; Wei, L.; Liu, C.X.; Fu, B.S.; Wang, J.Q.; Yang, X.R.; Liu, Y.N.; Liu, S.M.; Tian, T.; Zhou, X. Cucurbit[7]uril-driven host-guest chemistry for reversible intervention of 5-formylcytosine-targeted biochemical reactions. J. Am. Chem. Soc., 2017, 139, 16903-16912.
[15]
Guagnini, F.; Antonik, P.M.; Rennie, M.L.; O’Byrne, P.; Khan, A.R.; Pinalli, R.; Dalcanale, E.; Crowley, P.B. Cucurbit[7]uril-dimethyllysine recognition in a model protein. Angew. Chem. Int. Ed., 2018, 57, 7126-7130.
[16]
Jang, Y.; Jang, M.; Kim, H.; Lee, S.J.; Jin, E.; Koo, J.Y.; Hwang, I.C.; Kim, Y.; Ko, Y.H.; Hwang, I.; Oh, J.H.; Kim, K. Point-of-use detection of amphetamine-type stimulants with host-molecule-functionalized organic transistors. Chem, 2017, 3, 641-651.

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