Single Probiotic versus Multiple Probiotics - A Debate On Current Scenario for Alleviating Health Benefits

Title:Single Probiotic versus Multiple Probiotics - A Debate On Current Scenario for Alleviating Health Benefits

Volume: 24 Issue: 35

Author(s): Siva K. Korada, Nagendra S. Yarla, Vijayendra Mishra, Mohamed A. Daim, Bechan Sharma, Ashraf GM, Reggi R., Palmery M, Ilaria Peluso and Mohammad A. Kamal*

Affiliation:

• King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589,Saudi Arabia

Keywords: Probiotics, health benefits, single strain, safety recommendation, multiple probiotics, gut microbiota.

Abstract: Strain, dose, duration, validated clinical trial studies and scientific substantiation of health claims are needed in order to define a successful probiotic. In particular, the potency of probiotic differs from strain to strain. In this view, we aimed to know whether the single strain or multi-strain construct is more beneficial. We found that the studies were still under debate and mechanisms remain sometimes unclear. No conclusion can be made based on the strain experimentation. Safety data and significant statistical results for efficacy via well-controlled clinical trials are needed.

Cite this article as:

Korada K. Siva , Yarla S. Nagendra , Mishra Vijayendra, Daim A. Mohamed , Sharma Bechan , GM Ashraf , R. Reggi , M Palmery , Peluso Ilaria and Kamal A. Mohammad *, Single Probiotic versus Multiple Probiotics - A Debate On Current Scenario for Alleviating Health Benefits, Current Pharmaceutical Design 2018; 24 (35) . https://dx.doi.org/10.2174/1381612824666181012124136