Abstract
Background: Hybrids, composed of silver nanoparticles (AgNPs) dispersed inside a polymer matrix thus combining properties of both the components offer antibacterial activity and several advantages. Nevertheless, the development of antibacterial hybrid material comprising both novolac type phenolic resin and AgNPs remains one of the untouched issues in human healthcare.
Objective: We report herein the simple preparation of hybrid derived from functionalized novolac resin and AgNPs. The hybrid was tested for antibacterial activity towards Gram-positive and Gramnegative bacteria.
Method and Results: Preparation and characterization of functionalized novolac resin and hybrid were achieved. Gram-positive bacteria (Staphylococcus aureus MTCC 3160, Staphylococcus epidermidis NCIM2493, Bacillus subtilis) and Gram-negative bacteria (Pseudomonas aeruginosa ATCC27853, Escherichia coli) were used to test the bactericidal efficiency of hybrid. The antibacterial effectiveness of hybrid was determined in terms of the minimum inhibitory concentration (MIC). In addition, treatment with hybrid caused cytoplasmic contents leakage evidencing membrane damage.
Conclusion: The hybrid developed thus could provide opportunities to fabricate a wide range of antibacterial functional materials for different purposes in human health associated sectors.
Keywords: Antibacterial material, diethanolamine, functionalized novolac polymer, hybrid, minimum inhibitory concentration (MIC), silver nanoparticles.
Graphical Abstract
[1]
Hsiao M, Chen S, Shieh D, Yeh C. One-Pot synthesis of hollow Au3Cu1 spherical-like and biomineral botallackite Cu2(OH)3Cl flowerlike architectures exhibiting antimicrobial activity. J Phys Chem B 2006; 110: 205-10.
[2]
Jiang T, Liu L, Yao J. In situ deposition of silver nanoparticles on the cotton fabrics. Fibers Polym 2011; 12: 620-5.
[3]
Hatamie A, Khan A, Golabi M, et al. Zinc oxide nanostructure-modified textile and its application to biosensing, photocatalysis, and as antibacterial material. Langmuir 2015; 31: 10913-21.
[4]
Sykora D, Kasicka V, Miksik I, et al. Application of gold nanoparticles in separation sciences. J Sep Sci 2010; 30: 372-87.
[5]
Azam A, Ahmed AS, Oves M, Khan MS, Habib SS, Memic A. Antimicrobial activity of metal oxide nanoparticles against Gram-positive and Gram-negative bacteria: A comparative study. Int J Nanomedicine 2012; 7: 6003-9.
[6]
Giannousi K, Sarafidis G, Mourdikoudis S, Pantazaki A, Dendrinou-Samara C. Selective synthesis of Cu2O and Cu/Cu2O NPs: Antifungal activity to yeast saccharomyces cerevisiae and DNA interaction. Inorg Chem 2014; 53: 9657-66.
[7]
Sadiq IM, Chowdhury B, Chandrasekaran N, Mukherjee A. Antimicrobial sensitivity of Escherichia coli to alumina nanoparticles. Nanomedicine Nanotechnol Biol Med 2009; 5: 282-6.
[8]
Hajipour MJ, Fromm KM, Ashkarran AA, et al. Antibacterial properties of nanoparticles. Trends Biotechnol 2012; 10: 499-511.
[9]
Jin T, He Y. Antibacterial activities of magnesium oxide (MgO) nanoparticles against foodborne pathogens. J Nanopart Res 2011; 13: 6877-85.
[10]
Dizaj SM, Lotfipour F, Barzegar-Jalali M, Zarrintan MH, Adibkia K. Antimicrobial activity of the metals and metal oxides nanoparticles. Mater Sci Eng C 2014; 44: 278-84. [and references therein].
[11]
Li Q, Mahendra S, Lyon DY, et al. Antimicrobial nanomaterials for water disinfection and microbial control: Potential applications and implications. Water Res 2008; 42: 4591-602.
[12]
Bumbudsanpharoke N, Ko S. Nano-food packaging: An overview of market, migration research, and safety regulations. J Food Sci 2015; 80: R910-23.
[13]
Modjinou T, Rodriguez-Tobias H, Morales G, et al. UV-cured thiol-ene eugenol/ZnO composite materials with antibacterial properties. RSC Adv 2016; 6: 88135-42.
[14]
Wu P, Gao Y, Zhang H, Cai C. Aptamer-guided silver-gold bimetallic nanostructures with highly active surface-enhanced raman scattering for specific detection and near-infrared photothermal therapy of human breast cancer cells. Anal Chem 2012; 84: 7692-9.
[15]
Besinis A, De Peralta T, Handy RD. The antibacterial effects of silver, titanium dioxide and silica dioxide nanoparticles compared to the dental disinfectant chlorhexidine on streptococcus mutans using a suite of bioassays. Nanotoxicol 2014; 8: 1-16.
[16]
Raghunath A, Perumal E. Metal oxide nanoparticles as antimicrobial agents: A promise for the future. Int J Antimicrob Agents 2017; 49: 137-52. [and references therein].
[17]
Morones JR, Elechiguerra JL, Camacho A, et al. The bactericidal effect of silver nanoparticles. Nanotechnol 2005; 16: 2346-53.
[18]
Lee HY, Park HK, Kim K, Park SB. A practical procedure for producing silver nanocoated fabric and its antibacterial evaluation for biomedical applications. Chem Commun 2007; 28: 2959-61.
[19]
Elliott C. The effects of silver dressings on chronic and burns wound healing. Br J Nurs 2010; 19: 32-6.
[20]
Marambio-Jones C, Hoek EMV. A review of the antibacterial
effects of silver nanomaterials and potential implications for human
health and the environment. J Nanopart Res 2010; 12: 1531-55 references
therein
[21]
Garcıa-Contreras R, Argueta-Figueroa L, Mejıa-Rubalcava C, et al. Perspectives for the use of silver nanoparticles in dental practice. Int Dent J 2011; 61: 297-301.
[22]
Taglietti A, Diaz Fernandez YA, Amato E, et al. Antibacterial activity of glutathione-coated silver nanoparticles against Gram positive and Gram negative bacteria. Langmuir 2012; 28: 8140-8. [and references therein].
[23]
Gianluigi F, Annarita F, Stefania G, et al. Silver nanoparticles as potential antibacterial agents. Molecules 2015; 20: 8856-74.
[24]
Zhang Q, Ye J, Tian P, et al. Ag/TiO2 and Ag/SiO2 composite spheres: Synthesis, characterization and antibacterial properties. RSC Adv 2013; 3: 9739-44.
[25]
Nejad AG, Park CH, Kim CS. In situ synthesis of antimicrobial silver nanoparticles within antifouling zwitterionic hydrogels by catecholic redox chemistry for wound healing application. Biomacromolecules 2016; 17: 1213-23.
[26]
Noronha VT, Paula AJ, Duran G, et al. Silver nanoparticles in Dentistry. Dent Mater 2017; 33: 1110-26. [and references therein].
[27]
Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M. Broad-spectrum bioactivities of silver nanoparticles: The emerging trends and future prospects. Appl Microbiol Biotechnol 2014; 98: 1951-61.
[28]
Rai M, Yadav A, Gade A. Silver nanoparticles as a new generation of antimicrobials. Biotechnol Adv 2009; 27: 76-83.
[29]
Skladanowski M, Golinska P, Rudnicka K, Dahm H, Rai M. Evaluation of cytotoxicity, immune compatibility and antibacterial activity of biogenic silver nanoparticles. Med Microbiol Immunol 2016; 205: 603-13.
[30]
dos Santos CA, Seckler MM, Ingle AP, et al. Silver nanoparticles: therapeutical uses, toxicity, and safety issues. J Pharm Sci 2014; 103: 1931-44.
[31]
Aymonier C, Schlotterbeck U, Antonietti L, et al. Hybrids of silver nanoparticles with amphiphilic hyperbranched macromolecules exhibiting antimicrobial properties. Chem Commun 2002; 3018-9.
[32]
Singh AK, Tripathi M, Srivastava ON, Verma RK. Silver nanoparticles/gelatin composite: A new class of antibacterial material. ChemistrySelect 2017; 2: 7233-8.
[33]
Bokern S, Fan Z, Mattheis C, Greiner A, Agarwal S. Synthesis of new thermoplastic elastomers by silver nanoparticles as cross-linker. Macromolecules 2011; 44: 5036-42.
[34]
Vodnik VV, Božanic DK, Džunuzovic E, Vukovic J, Nedeljkovic JM. Thermal and optical properties of silver-poly(methylmethacrylate) nanocomposites prepared by in-situ radical polymerization. Eur Polym J 2010; 46: 137-44.
[35]
Chook SW, Chia CH, Zakaria S, Neoh HM, Jamal R. Effective immobilization of silver nanoparticles on a regenerated cellulose-chitosan composite membrane and its antibacterial activity. New J Chem 2017; 41: 5061-5.
[36]
Dallas P, Sharma VK, Zboril R. Silver polymeric nanocomposites as advanced antimicrobial agents: Classification, synthetic paths, applications, and perspectives. Adv Colloid Interface Sci 2011; 166: 119-35. [and references therein].
[37]
Singh R, Singh D, Singh A. Antimicrobial evaluation of silver nanoparticle-polymer composites prepared by gamma radiation. American J Polym Sci Tech 2016; 2: 40-6.
[38]
Zhang S, Tang Y, Vlahovic BA. Review on preparation and applications of silver-containing nanofibers. Nanoscale Res Lett 2016; 11: 80-8. [and references therein].
[39]
Toker RD, Kayaman-Apohan N, Kahraman MV. UV-curable nano-silver containing polyurethane based organic-inorganic hybrid coatings. Prog Org Coat 2013; 76: 1243-50.
[40]
Annur D, Wang ZK, Liao JD, Kuo C. Plasma-synthesized silver nanoparticles on electrospun chitosan nanofiber surfaces for antibacterial applications. Biomacromolecules 2015; 16: 3248-55.
[41]
Crespy D, Bozonnet M, Meier M. 100 years of bakelite, the material of a 1000 uses. Angew Chem Int Ed 2008; 47: 3322-8.
[42]
Konishi G. Precision polymerization of designed phenol: New aspects of phenolic resin chemistry. J Syn Org Chem Jpn 2008; 66: 705-13.
[43]
Chang X, Li M, Liu Q, Liu Q, Yao J. Adsorption-reduction of chromium(VI) from aqueous solution by phenol-formaldehyde resin microspheres. RSC Adv 2016; 6: 46879-88. [and references therein].
[44]
Ghosh S, Acharyya M, Manna R, Dey CK. Removal of azo dye molecules from aqueous solution using novolac resin based network polymer. Bull Chem Soc Jpn 2011; 84: 349-51.
[45]
Ghosh S, Acharyya M. Design of novolac resin-based network polymers for adsorptive removal of azo dye molecules. RSC Adv 2016; 6: 28781-6.
[46]
Performance Standards for Antimicrobial Susceptibility Testing 20th Informational Supplement, CLSI document M100-S20-U.
Wayne, PA: Clinical and Laboratory Standard Institute . 2010.
[47]
Samanta T, Roymahapatra G, Porto WF, et al. N, N′-Olefin functionalized bis-imidazolium gold(I) salt is an efficient candidate to control keratitis-associated eye infection. PLoS One 2013; 8(3): e58346.
[48]
Sahu K, Bansal H, Mukherjee C, Sharma M, Gupta PK. Atomic force microscopic study on morphological alterations induced by photodynamic action of toluidine blue O in Staphylococcus aureus and Escherichia coli. J Photochem Photobiol B 2009; 96: 9-16.
[49]
Haes AJ, van Duyne RP. A nanoscale optical biosensor: Sensitivity and selectivity of an approach based on the localized surface plasmon resonance spectroscopy of triangular silver nanoparticles. J Am Chem Soc 2002; 124: 10596-604.
[50]
Raveendran P, Fu J, Wallen SL. Completely “Green” synthesis and stabilization of metal nanoparticles. J Am Chem Soc 2003; 125: 13940-1.
[51]
Karthikeyan B. Spectroscopic studies on Ag-polyvinyl alcohol nanocomposite films. Physica B 2005; 364: 328-32.
[52]
Zheng J, Stevenson MS, Hikida RS, Patten PGV. Influence of pH on dendrimer-protected nanoparticles. J Phys Chem B 2002; 106(6): 1252-5.
[53]
Gupta S, Uhlmann P, Agrawal M, Chapuis S, Oertel U, Stamm M. Immobilization of silver nanoparticles on responsive polymer brushes. Macromolecules 2008; 41: 2874-9.
[54]
Morones JR, Elechiguerra JL, Camacho A, et al. The bactericidal effect of silver nanoparticles. Nanotechnology 2005; 16(10): 2346-53.
[55]
Agnihotri S, Mukherji S, Mukherji S. Size-controlled silver nanoparticles synthesized over the range 5-100 nm using the same protocol and their antibacterial efficacy. RSC Adv 2014; 4: 3974-83.
[56]
Bera RK, Mandal SM, Raj CR. Antimicrobial activity of fluorescent Ag nanoparticles. Lett Appl Microbiol 2014; 58: 520-6.
[57]
Zille A, Fernandes MM, Francesko A, et al. Size and aging effects on antimicrobial efficiency of silver nanoparticles coated on polyamide fabrics activated by atmospheric DBD. ACS Appl Mater Interfaces 2015; 7: 13731-44.
[58]
Bernabo M, Pucci A, Galembeck F, de Paula Leite CA, Ruggeri G. Thermal- and sun-promoted generation of silver nanoparticles embedded into poly(vinyl alcohol) films. Macromol Mater Eng 2009; 294: 256-64.
[59]
Shrivastava S, Bera T, Roy A, Singh G, Ramachandrarao P, Dash D. Characterization of enhanced antibacterial effects of novel silver nanoparticles. Nanotechnology 2007; 18: 103-12.
[60]
Duran N, Duran M, de Jesus MB, Seabra AB, Favaro WJ, Nakazato G. Silver nanoparticles: A new view on mechanistic aspects on antimicrobial activity. Nanomedicine 2016; 12(3): 789-99.
[61]
AshaRani PV. Mun GLK, Hande MP, Valiyaveettil S. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 2009; 3: 279-90.
[62]
Matsumura Y, Yoshikata K, Kunisaki S, Tsuchido T. Mode of bactericidal action of silver zeolite and its comparison with that of silver nitrate. Appl Environ Microbiol 2003; 69: 4278-81.
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