Abstract
Carboxylic acids are one type of the most common, readily available and structural diverse synthetic sources which gradually serve as versatile connection points in organic transformations. The decarboxylative reaction of carboxylic acids has attracted great attention in providing an efficient and powerful strategy for the construction of various valuable molecular skeletons. Over the past decades, a number of obvious and satisfactory achievements in the field have constantly emerged. The review mainly introduces recent advances on the decarboxylative reactions based on aliphatic, alkenylic or carbonic, aromatic and alkynylic acids as decarboxylative partners for the functionalization of C(sp3)-H, C(sp2)-H and C-heteroatom bonds since 2011.
Keywords: Carboxylic acid, decarboxylative reaction, coupling reaction, radical oxidative, functionalization, organic transformation.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
51
5