摘要
背景：越来越多的证据表明微生物在宿主的稳态过程中起着重要的作用。到目前为止，研究人员主要集中在细菌微生物区系的作用上。然而，人类肠道是几种真菌的栖息地，产生大量的代谢产物。此外，各种食物和饮料中含有丰富的真菌及其代谢物。方法：检索PubMed和Google学者数据库，对真菌代谢产物、人类真菌群组成和真菌失调进行临床和临床前研究。结果：真菌代谢产物可作为信号分子发挥重要的生物学作用，包括营养、抗炎或抗菌作用。最后，研究表明肠道真菌成分的变化与人类健康之间存在关联。在肥胖症、肝炎和炎症性肠病中发现了真菌群组成的变化。结论：真菌和膳食真菌对哺乳动物体内稳态的影响可能包括益生菌和粪便移植治疗。此外，真菌衍生分子的抗菌作用可作为食品工业中常用抗菌剂和防腐剂的替代物。
关键词: 真菌群，真菌代谢物，益生菌，粪便移植，肠道。
图形摘要
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