Synthesis of Fluoroalkyl Substituted Heterocycles Using Fluorinecontaining Building Blocks

Title: Synthesis of Fluoroalkyl Substituted Heterocycles Using Fluorinecontaining Building Blocks

Volume: 6 Issue: 12

Author(s): S. Z. Zhu, Y. L. Wang, W. M. Peng, L. P. Song and G. F. Jin

Affiliation:

Keywords: Fluoroalkyl, Heterocycles, alkenes and alkynes, 3-Fluoro-3-Fluoroalkylacrylates, pyridinum

Abstract: This review deals with recent progress in the synthesis of fluorine-containing heterocyclic compounds using the fluorinated building block method. Several fundamental fluorinated building blocks such as fluorinecontaining multiple bond compounds, fluoroalkyl substituted carbonyl compounds are described in detail, they are readily prepared and easy to scale up from the commercial available starting materials such as RfX, RfCXYZ (X, Y, Z: halogen), (CF3CO)2O etc. Under mild reaction condition, they react with various organic reagents to give a variety fluoroalkyl substituted N, S, O-heterocycles.

Cite this article as:

Zhu Z. S., Wang L. Y., Peng M. W., Song P. L. and Jin F. G., Synthesis of Fluoroalkyl Substituted Heterocycles Using Fluorinecontaining Building Blocks, Current Organic Chemistry 2002; 6 (12) . https://dx.doi.org/10.2174/1385272023373635