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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Synthesis of Trifluoromethyl Ketones Using Polymer-Supported Reagents

Author(s): I. R. Baxendale, S. V. Ley, W. Lumeras and M. Nesi

Volume 5, Issue 3, 2002

Page: [197 - 199] Pages: 3

DOI: 10.2174/1386207024607220

Price: $65

Abstract

A two step synthesis of trifluoromethyl ketones from aldehydes is reported. A combination of polymer-supported reagents and sequestering agents were employed to effect the transformation without the need for chromatographic purification.

Keywords: polymer-supported reagent, sequestering agent, multi-parallel synthesis

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