Abstract
Background: Progesterone is a sex steroid hormone. Since it has been discovered, it is widely used in the prevention of spontaneous preterm birth, hormone replacement therapy and other gynecological conditions.
Methods: We will review the progesterone preparations based on a comprehensive study of papers and patents from the traditional preparations up through the very recent literatures.
Results: This review mainly concentrates on oral, vaginal and micro delivery systems, involving different ways to prepare progesterone preparations.
Conclusion: Although progesterone has first-pass effects, with these methods, the bioavailability and compliance can be greatly increased.
Keywords: Delivery system, injection, microspheres, oral, progesterone preparations, vaginal.
Graphical Abstract
Related Books
Localized Micro/Nanocarriers for Programmed and On-Demand Controlled Drug Release
Mixed Polymeric Micelles for Osteosarcoma Therapy: Development and Characterization
A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems
Nanomaterials: Evolution and Advancement towards Therapeutic Drug Delivery (Part II)
Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery (Part I)
49
3