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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

Iron Mediated Desulfurization and C-N Bond Formation: Strategy for the Synthesis of Thioureas

Author(s): Venkata Bhavanarushi Pendem and Madhavi Nannapaneni*

Volume 15, Issue 12, 2018

Page: [1025 - 1029] Pages: 5

DOI: 10.2174/1570178615666180412110323

Price: $65

Abstract

A highly efficient and simple protocol for the construction of aromatic and aliphatic thioureas from their respective amines in the presence of cheap, readily available and air-stable iron catalyst in one pot three steps reaction is described. All the reactions were carried out under optimized reaction conditions to get the target products in good to excellent yields and shorter reaction time.

Keywords: Anilines, iron catalyst, thiocarbamate, thioureas, C-N bond formation, heterocycle.

Graphical Abstract


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