Abstract
Background: Due to significant biological activity associated with N-, O- and Sheterocycles, a number of reports for their synthesis have appeared in recent decades. Traditional approaches require expensive or highly specialized equipment or would be of limited use to the synthetic organic chemist due to their highly inconvenient approaches. This review summarizes the applications of platinum metal with emphasis of their synthetic applications for heterocylces. In summary, this review article describes the synthesis of different sized heterocyclic rings containing different heteroatoms.
Objective: The key area of research these days is the development of rapid, efficient and versatile tools for the construction of heterocycles and much prominence was gained by protocols that involved transition- metal catalysis. The traditional strategies that involved long reaction times, harsh conditions and limited substrate scopes are overshadowed by these catalytic practices.
Conclusion: The efficient and chemoselective synthesis of heterocycles by this technique has appeared as an important tool. This review shows a highly dynamic research field and the employment of platinum catalysts in organic synthesis. Several strategies have been pointed out in the past few years, to meet more sustainable, efficient and environmentally benign chemical products and procedures. The catalytic strategies have been the focus of intense research because they avoid the use of toxic reagents. Among these catalytic strategies, highly rewarding and an important method in heterocycles synthesis is metal catalyzed synthesis.
Keywords: Platinum, catalysis, heterocycles, transition metals, synthesis, biological activity.
Graphical Abstract
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