Abstract
Background: The reaction of aryl halides or vinyl halides with activated alkenes in the presence of Palladium-catalyst along with a base for the formation of the C-C bond is called the Heck reaction. This reaction has been employed extensively in the synthesis of heterocyclic compounds.
Methodology: We have highlighted these applications in 2010.
Conclusion: This review aims to cover the recent application of the Heck reaction in the synthesis of heterocyclic compounds during a period from 2010 to 2017.
Keywords: Heck reaction, heterocyclic compounds, Pd, palladium, carbon-carbon bond formation, catalysis.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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