Polymeric Nanocarriers: A New Horizon for the Effective Management of Breast Cancer

Title:Polymeric Nanocarriers: A New Horizon for the Effective Management of Breast Cancer

Volume: 23 Issue: 35

Author(s): Iliyas Khan, Hitesh Kumar, Gaurav Mishra, Avinash Gothwal, Prashant Kesharwani and Umesh Gupta*

Affiliation:

• Department of Pharmacy, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Bandarsindri, Ajmer, Rajasthan-305817,India

Keywords: Nano-carriers, breast cancer, polymeric micelles, polymeric nanoparticles, dendrimers, liposomes, nanoshells, quantum dots.

Abstract: Background: Delivery of chemotherapeutic drugs for the diagnosis and treatment of cancer is becoming advanced day by day. However, the challenge of the effective delivery system still does exist. In various types of cancers, breast cancer is the most commonly diagnosed cancer among women. Breast cancer is a combination of different diseases. It cannot be considered as only one entity because there are many specific patient factors, which are involved in the development of this disease. Nanotechnology has opened a new area in the effective treatment of breast cancer due to the several benefits offered by this technology.

Methods: Polymeric nanocarriers are among one of the effective delivery systems, which has given promising results in the treatment of breast cancers. Nanocarriers does exert their anticancer effect either through active or passive targeting mode.

Results: The use of nanocarriers has been resolute about the adverse effects of chemotherapeutic drugs such as poor solubility and less penetrability in tumor cells.

Conclusion: The present review is focused on recent developments regarding polymeric nanocarriers, such as polymeric micelles, polymeric nanoparticles, dendrimers, liposomes, nanoshells, fullerenes, carbon nanotubes (CNT) and quantum dots, etc. for their recent advancements in breast cancer therapy.

Cite this article as:

Khan Iliyas , Kumar Hitesh, Mishra Gaurav , Gothwal Avinash , Kesharwani Prashant and Gupta Umesh *, Polymeric Nanocarriers: A New Horizon for the Effective Management of Breast Cancer, Current Pharmaceutical Design 2017; 23 (35) . https://dx.doi.org/10.2174/1381612823666170829164828