Abstract
2,4,5-Triaryl-1H-imidazoles were synthesized from benzyl bromides under Kornblum oxidative condition. The reaction proceeded via an in situ oxidation followed by condensation to afford the desired products in good yields.
Keywords: Imidazoles, Kornblum oxidation, benzyl halide, one-pot, three-component reaction, MCRs.
Graphical Abstract
Letters in Organic Chemistry
Title:Synthesis of 2,4,5-Triaryl-1H-Imidazoles under Kornblum Oxidative Condition
Volume: 15 Issue: 6
Author(s): Mohammad Hosein Sayahi, Mina Bahmei, Setareh Moghimi, Mohammad Mahdavi, Loghman Firoozpour and Alireza Foroumadi*
Affiliation:
- Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran,Iran
Keywords: Imidazoles, Kornblum oxidation, benzyl halide, one-pot, three-component reaction, MCRs.
Abstract: 2,4,5-Triaryl-1H-imidazoles were synthesized from benzyl bromides under Kornblum oxidative condition. The reaction proceeded via an in situ oxidation followed by condensation to afford the desired products in good yields.
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Cite this article as:
Sayahi Hosein Mohammad , Bahmei Mina , Moghimi Setareh , Mahdavi Mohammad , Firoozpour Loghman and Foroumadi Alireza *, Synthesis of 2,4,5-Triaryl-1H-Imidazoles under Kornblum Oxidative Condition, Letters in Organic Chemistry 2018; 15 (6) . https://dx.doi.org/10.2174/1570178614666170726125544
DOI https://dx.doi.org/10.2174/1570178614666170726125544 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |

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