Abstract
The focus of this review is to simplify the role of acyl donor (P1) and the nucleophile (P1) in an enzymatic reaction. The specificity of P1 and P1 is described and arranged in order. In this review, the relationship between the amino acid and enzyme is linked to facilitate the selection of an enzyme to catalyze the synthesis of the desired peptides.
Keywords: Enzymatic Peptide, acyl donor, nucleophile
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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